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Table 6 Univariate and multivariate of secondary composite outcome

From: Urine albumin dipstick independently predicts cardiovascular and renal outcomes among rural Thai population: a 14-year retrospective cohort study

Baseline variables

Univariate

Multivariate

Crude HR (95%CI)

p-value

Adjusted HRa (95%CI)

p-value

Normoalbuminuria

Reference

1

Reference

1

Microalbuminuria

1.2 (0.84, 1.71)

0.312

1.14 (0.75, 1.73)

0.549

Macroalbuminuria

2.23 (1.26, 3.97)

0.006

1.92 (0.9, 4.08)

0.09

Age (years)

1.04 (1.03, 1.06)

< 0.001

1.05 (1.02, 1.07)

< 0.001

Male (%)

1.45 (1.07, 1.97)

0.016

1.21 (0.82, 1.79)

0.335

BMI (kg/m2)

1.02 (0.97, 1.07)

0.414

  

Systolic BP (mmHg)

1 (0.99, 1.01)

0.44

  

Diastolic BP (mmHg)

0.99 (0.98, 1.01)

0.439

  

History of Hypertension

2.08 (1.53, 2.84)

< 0.001

1.9 (1.16, 3.11)

0.011

History of Type2 DM

2.12 (1.43, 3.15)

< 0.001

1.59 (0.6, 4.2)

0.346

History of Dyslipidemia

1.08 (0.63, 1.83)

0.786

  

History of smoking (%)

1.18 (0.82, 1.7)

0.373

  

Serum creatinine (mg/dL)

2.92 (1.35, 6.3)

0.007

  

eGFR (ml/min/1.73m2)

0.98 (0.97, 0.99)

< 0.001

1 (0.99, 1.01)

0.817

Aspirin (use)

3.21 (2.17, 4.75)

< 0.001

2.08 (1.2, 3.6)

0.009

ACEI/ARBs (use)

1.93 (1.32, 2.81)

0.001

0.93 (0.53, 1.61)

0.786

Insulin (use)

3.42 (1.8, 6.49)

< 0.001

1.13 (0.47, 2.7)

0.785

Metformin (use)

1.8 (1.15, 2.83)

0.01

0.47 (0.18, 1.25)

0.131

  1. Secondary composite outcome includes cardiovascular or renal morbidity and all-cause mortality
  2. BMI Body mass index, BP Blood pressure, DM Diabetes mellitus, eGFR Estimated glomerular filtration rate, ACEI/ARBs Angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers. All variables are at baseline level
  3. aAdjusted by age, gender, type 2 diabetes, hypertension, eGFR, Aspirin, ACEI/ARBs, Insulin and Metformin