Baseline variables | Univariate | Multivariate | ||
---|---|---|---|---|
Crude HR (95%CI) | p-value | Adjusted HRa (95%CI) | p-value | |
Normoalbuminuria | Reference | 1 | Reference | 1 |
Microalbuminuria | 1.2 (0.84, 1.71) | 0.312 | 1.14 (0.75, 1.73) | 0.549 |
Macroalbuminuria | 2.23 (1.26, 3.97) | 0.006 | 1.92 (0.9, 4.08) | 0.09 |
Age (years) | 1.04 (1.03, 1.06) | < 0.001 | 1.05 (1.02, 1.07) | < 0.001 |
Male (%) | 1.45 (1.07, 1.97) | 0.016 | 1.21 (0.82, 1.79) | 0.335 |
BMI (kg/m2) | 1.02 (0.97, 1.07) | 0.414 | Â | Â |
Systolic BP (mmHg) | 1 (0.99, 1.01) | 0.44 | Â | Â |
Diastolic BP (mmHg) | 0.99 (0.98, 1.01) | 0.439 | Â | Â |
History of Hypertension | 2.08 (1.53, 2.84) | < 0.001 | 1.9 (1.16, 3.11) | 0.011 |
History of Type2 DM | 2.12 (1.43, 3.15) | < 0.001 | 1.59 (0.6, 4.2) | 0.346 |
History of Dyslipidemia | 1.08 (0.63, 1.83) | 0.786 | Â | Â |
History of smoking (%) | 1.18 (0.82, 1.7) | 0.373 | Â | Â |
Serum creatinine (mg/dL) | 2.92 (1.35, 6.3) | 0.007 | Â | Â |
eGFR (ml/min/1.73m2) | 0.98 (0.97, 0.99) | < 0.001 | 1 (0.99, 1.01) | 0.817 |
Aspirin (use) | 3.21 (2.17, 4.75) | < 0.001 | 2.08 (1.2, 3.6) | 0.009 |
ACEI/ARBs (use) | 1.93 (1.32, 2.81) | 0.001 | 0.93 (0.53, 1.61) | 0.786 |
Insulin (use) | 3.42 (1.8, 6.49) | < 0.001 | 1.13 (0.47, 2.7) | 0.785 |
Metformin (use) | 1.8 (1.15, 2.83) | 0.01 | 0.47 (0.18, 1.25) | 0.131 |