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Table 1 Classification categories and definitions in Pharao® and Renbase® [8,9,10]

From: Kidney function and nephrotoxic drug use among older home-dwelling persons with or without diabetes in Finland

Classification

Definition

Pharao

Renbase

A

No known pharmacological or clinical basis for an increased risk.

No need for dosage modification.

B

There is a somewhat increased risk.

The information is not available or the recommendation is estimated based on the pharmacokinetic characteristics of the substance.

C

There is a moderately increased risk.

Modification of the dose or dosage interval is needed.

D

There is a high risk.

The use should be avoided.

0

No pharmacological effect.

1

A mild pharmacological effect.

2

A moderate pharmacological effect.

3

A strong pharmacological effect.