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Table 3 Association of Post Transplant Erythrocytosis and patient & allograft survival

From: Contemporary incidence and risk factors of post transplant Erythrocytosis in deceased donor kidney transplantation

Outcome

Exposure

Number of event (%)

Mean event rate per 1000 patient year (95% CI)

Unadjusted Hazard Ratio (95% CI)

Adjusted 1 Hazard Ratio (95% CI)

Adjusted 2 Hazard Ratio (95% CI)

Death

No PTE (n = 1048)

103 (10%)

23.5 (19.4, 28.5)

1 (ref)

1 (ref)

1 (ref)

PTE (n = 75)

4 (5%)

18.4 (6.9, 48.9)

0.88 (0.32, 2.41)

1.01 (0.50, 2.07)

1.07 (0.52, 2.20)

All-cause graft failure

No PTE (n = 1048)

228a (22%)

52.0 (45.6, 59.2)

1 (ref)

1 (ref)

1 (ref)

PTE (n = 75)

8 (11%)

36.7 (18.4, 73.4)

0.81 (0.40, 1.64)

1.07 (0.39, 2.94)

1.29 (0.46, 3.63)

Death-censored graft failure

No PTE (n = 1048)

131 (12%)

29.9 (25.2, 35.4)

1 (ref)

1 (ref)

1 (ref)

PTE (n = 75)

4 (5%)

18.4 (6.9, 48.9)

0.72 (0.27, 1.98)

0.94 (0.35, 2.60)

0.94 (0.34, 2.60)

  1. Adjusted 1 is adjusted for donor Kidney Donor Profile Index (KDPI)
  2. Adjusted 2 is adjusted for donor KDPI, cold ischemia time and the following recipient variables: age (years), black race, sex, previous kidney transplant, number of human leukocyte antigen mismatches, panel reactive antibody (%), body mass index (kg/m2), preemptive transplant and transplant center
  3. aThere were 6 recipients who developed graft failure and then died. This explains the difference between the number of all-cause graft failure (228) and the sum of numbers of death (103) and death-censored graft failure (131)