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Table 3 Comparison of general data according to the location of immunofluorescence deposits at diagnosis

From: Immunofluorescence deposits in the mesangial area and glomerular capillary loops did not affect the prognosis of immunoglobulin a nephropathy except C1q:a single-center retrospective study

Parameters N Age (years) Female (n, %) Weight (kg) SBP (mmHg) DBP (mmHg) MAP (mmHg)
IgA Mesangial-only 251 30.0 (24.0,39.0) 143 (56.9) 58.7 ± 10.8 124.6 ± 16.2 79.9 ± 12.5 94.8 ± 12.7
Mesangial +GCLs 86 32.0 (23.0,42.2) 49 (57.0) 61.6 ± 12.1* 129.2 ± 16.8* 81.8 ± 11.8 97.6 ± 12.4
P   0.697 0.999 0.040 0.037 0.223 0.077
IgG (−) 258 30.0 (24.0,39.0) 146 (56.5) 59.4 ± 11.2 125.5 ± 16.6 80.1 ± 13.0 95.2 ± 13.1
Mesangial-only 32 29.0 (24.2,40.7) 17 (53.1) 59.0 ± 10.6 123.9 ± 15.4 79.7 ± 10.1 94.4 ± 11.0
Mesangial +GCLs 33 32.0 (21.0,45.5) 22 (66.7) 60.9 ± 13.3 130.0 ± 18.2 83.2 ± 10.5 98.8 ± 12.1
P   0.962 0.482 0.897 0.329 0.277 0.293
IgM (−) 199 31.0 (24.0,40.0) 106 (53.3) 59.1 ± 11.0 125.5 ± 16.3 80.2 ± 12.6 95.3 ± 12.8
Mesangial-only 102 29.5 (24.0,39.2) 63 (61.8) 60.0 ± 11.7 125.2 ± 17.0 79.9 ± 11.6 95.0 ± 12.3
Mesangial +GCLs 35 29.0 (24.0,39.0) 22 (62.8) 60.0 ± 11.3 129.2 ± 16.0 82.1 ± 12.6 97.8 ± 13.1
P   0.981 0.279 0.729 0.407 0.736 0.554
C3 (−) 162 31.5 (23.0,40.2) 86 (53.1) 60.3 ± 11.8 126.0 ± 16.7 80.7 ± 12.5 95.8 ± 12.9
Mesangial-only 127 29.0 (24.0,37.0) 78 (61.4) 58.5 ± 10.5 123.6 ± 15.5 78.6 ± 11.4 93.6 ± 11.5
Mesangial +GCLs 46 36.5 (24.0,40.5) 26 (56.5) 59.5 ± 11.3 131.2 ± 17.4b 83.9 ± 13.8 99.7 ± 14.3
P   0.619 0.367 0.390 0.028 0.110 0.052
Fib (−) 299 29.0 (24.0,38.0) 171 (57.2) 59.2 ± 11.0 125.6 ± 16.0 80.2 ± 12.5 95.3 ± 12.6
Mesangial-only 17 39.0 (30.0,41.0) 11 (64.7) 59.0 ± 11.0 124.0 ± 18.7 83.1 ± 10.6 96.7 ± 12.7
Mesangial +GCLs 19 39.0 (23.0,44.0) 9 (47.4) 63.4 ± 13.9 131.8 ± 20.8 82.0 ± 11.6 98.6 ± 14.1
P   0.068 0.568 0.469 0.318 0.345 0.512
C1q (−) 303 30.0 (24.0,39.0) 175 (57.7) 59.2 ± 11.0 125.1 ± 15.7 80.1 ± 12.0 95.1 ± 12.2
Mesangial-only 19 35.0 (24.0,42.0) 10 (52.6) 61.2 ± 12.2 130.8 ± 24.3 80.8 ± 14.0 97.5 ± 16.6
Mesangial +GCLs 14 27.5 (24.5,43.2) 7 (50.0) 62.7 ± 14.0 133.2 ± 17.8 86.1 ± 16.0 101.8 ± 16.3
P   0.865 0.781 0.392 0.079 0.368 0.214
  1. Abbreviations: SBP systolic blood pressure, DBP diastolic blood pressure, MAP mean arterial pressure, Fib Fibrinogen, IgG (−) without IgG deposits, IgM (−) without IgM deposits, C3(−) without C3 deposits, Fib (−) without Fib deposits, C1q (−) without C1q deposits, GCLs glomerular capillary loops
  2. * P compare between the IgA groups
  3. a P compare with (−) group
  4. b P compare with the Mesangial-only group
  5. Statistically significant at P < 0.05
  6. The patients with immune deposits in the GCLs-only group were excluded due to the small sample size