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Table 3 Comparison of general data according to the location of immunofluorescence deposits at diagnosis

From: Immunofluorescence deposits in the mesangial area and glomerular capillary loops did not affect the prognosis of immunoglobulin a nephropathy except C1q:a single-center retrospective study

Parameters

N

Age (years)

Female (n, %)

Weight (kg)

SBP (mmHg)

DBP (mmHg)

MAP (mmHg)

IgA Mesangial-only

251

30.0 (24.0,39.0)

143 (56.9)

58.7 ± 10.8

124.6 ± 16.2

79.9 ± 12.5

94.8 ± 12.7

Mesangial +GCLs

86

32.0 (23.0,42.2)

49 (57.0)

61.6 ± 12.1*

129.2 ± 16.8*

81.8 ± 11.8

97.6 ± 12.4

P

 

0.697

0.999

0.040

0.037

0.223

0.077

IgG (−)

258

30.0 (24.0,39.0)

146 (56.5)

59.4 ± 11.2

125.5 ± 16.6

80.1 ± 13.0

95.2 ± 13.1

Mesangial-only

32

29.0 (24.2,40.7)

17 (53.1)

59.0 ± 10.6

123.9 ± 15.4

79.7 ± 10.1

94.4 ± 11.0

Mesangial +GCLs

33

32.0 (21.0,45.5)

22 (66.7)

60.9 ± 13.3

130.0 ± 18.2

83.2 ± 10.5

98.8 ± 12.1

P

 

0.962

0.482

0.897

0.329

0.277

0.293

IgM (−)

199

31.0 (24.0,40.0)

106 (53.3)

59.1 ± 11.0

125.5 ± 16.3

80.2 ± 12.6

95.3 ± 12.8

Mesangial-only

102

29.5 (24.0,39.2)

63 (61.8)

60.0 ± 11.7

125.2 ± 17.0

79.9 ± 11.6

95.0 ± 12.3

Mesangial +GCLs

35

29.0 (24.0,39.0)

22 (62.8)

60.0 ± 11.3

129.2 ± 16.0

82.1 ± 12.6

97.8 ± 13.1

P

 

0.981

0.279

0.729

0.407

0.736

0.554

C3 (−)

162

31.5 (23.0,40.2)

86 (53.1)

60.3 ± 11.8

126.0 ± 16.7

80.7 ± 12.5

95.8 ± 12.9

Mesangial-only

127

29.0 (24.0,37.0)

78 (61.4)

58.5 ± 10.5

123.6 ± 15.5

78.6 ± 11.4

93.6 ± 11.5

Mesangial +GCLs

46

36.5 (24.0,40.5)

26 (56.5)

59.5 ± 11.3

131.2 ± 17.4b

83.9 ± 13.8

99.7 ± 14.3

P

 

0.619

0.367

0.390

0.028

0.110

0.052

Fib (−)

299

29.0 (24.0,38.0)

171 (57.2)

59.2 ± 11.0

125.6 ± 16.0

80.2 ± 12.5

95.3 ± 12.6

Mesangial-only

17

39.0 (30.0,41.0)

11 (64.7)

59.0 ± 11.0

124.0 ± 18.7

83.1 ± 10.6

96.7 ± 12.7

Mesangial +GCLs

19

39.0 (23.0,44.0)

9 (47.4)

63.4 ± 13.9

131.8 ± 20.8

82.0 ± 11.6

98.6 ± 14.1

P

 

0.068

0.568

0.469

0.318

0.345

0.512

C1q (−)

303

30.0 (24.0,39.0)

175 (57.7)

59.2 ± 11.0

125.1 ± 15.7

80.1 ± 12.0

95.1 ± 12.2

Mesangial-only

19

35.0 (24.0,42.0)

10 (52.6)

61.2 ± 12.2

130.8 ± 24.3

80.8 ± 14.0

97.5 ± 16.6

Mesangial +GCLs

14

27.5 (24.5,43.2)

7 (50.0)

62.7 ± 14.0

133.2 ± 17.8

86.1 ± 16.0

101.8 ± 16.3

P

 

0.865

0.781

0.392

0.079

0.368

0.214

  1. Abbreviations: SBP systolic blood pressure, DBP diastolic blood pressure, MAP mean arterial pressure, Fib Fibrinogen, IgG (−) without IgG deposits, IgM (−) without IgM deposits, C3(−) without C3 deposits, Fib (−) without Fib deposits, C1q (−) without C1q deposits, GCLs glomerular capillary loops
  2. * P compare between the IgA groups
  3. a P compare with (−) group
  4. b P compare with the Mesangial-only group
  5. Statistically significant at P < 0.05
  6. The patients with immune deposits in the GCLs-only group were excluded due to the small sample size
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BMC Nephrology

ISSN: 1471-2369

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