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Table 6 Comparison of the Oxford classification according to the location of immunofluorescence deposits at diagnosis

From: Immunofluorescence deposits in the mesangial area and glomerular capillary loops did not affect the prognosis of immunoglobulin a nephropathy except C1q:a single-center retrospective study

Parameters N M1 (%) E1 (%) S1 (%) T (1 + 2) (%) C (1 + 2) (%)
IgA Mesangial-only 251 4.8 7.6 69.7 73.3 35.9
  Mesangial +GCLs 86 5.6 7.0 77.9 73.9 43.0
  P   0.244 0.856 0.145 0.679 0.237
IgG (−) 258 4.7 7.8 71.7 76.4 36.0
  Mesangial-only 32 6.3 9.4 68.8 56.3 a 43.8
  Mesangial +GCLs 33 15.2 a 6.1 78.8 69.7 42.4
  P   0.037 0.882 0.627 0.044 0.575
IgM (−) 199 6.0 9.5 69.8 77.9 42.2
  Mesangial-only 102 3.9 5.9 70.6 66.7 28.4
  Mesangial +GCLs 35 8.6 0.0 85.7 71.4 37.1
  P   0.553 0.108 0.150 0.105 0.065
C3 (−) 162 4.9 8.6 69.8 74.7 34.6
  Mesangial-only 127 4.7 6.3 70.9 74.8 40.2
  Mesangial +GCLs 46 10.9 6.5 80.4 69.6 41.3
  P   0.259 0.728 0.355 0.758 0.533
Fib (−) 299 6.4 8.0 70.9 75.3 36.8
  Mesangial-only 17 0.0 0.0 82.4 64.7 47.1
  Mesangial +GCLs 19 0.0 5.3 73.7 57.9 36.8
  P   0.297 0.440 0.583 0.171 0.695
C1q (−) 303 5.3 7.6 71.0 74.3 38.3
  Mesangial-only 19 5.3 10.5 84.2 68.4 36.8
  Mesangial +GCLs 14 7.1 0.0 71.4 71.4 21.4
  P   0.955 0.497 0.461 0.836 0.444
  1. Abbreviations: Fib Fibrinogen, IgG (−) without IgG deposits, IgM (−) without IgM deposits, C3(−) without C3 deposits, Fib (−) without Fib deposits, C1q (−) without C1q deposits, GCLs glomerular capillary loops, M mesangial hypercellularity, E endocapillary hypercellularity, S segmental glomerulosclerosis, T tubular atrophy/interstitial fibrosis, C Cellular or fibrocellular crescents
  2. * P compare between the IgA groups
  3. a P compare with (−) group
  4. b P compare with the Mesangial-only group
  5. Statistically significant at P < 0.05
  6. The patients with immune deposits in the GCLs group were excluded due to the small sample size