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Table 1 Baseline clinical characteristics by CKDc subgroups

From: Chronic kidney disease, atherosclerotic plaque characteristics on carotid magnetic resonance imaging, and cardiovascular outcomes

 

Non-CKDc Subgroup

(N = 269)

CKDc Subgroup

(N = 196)

P-value

Estimated GFRd, (ml/min/1.73 m2)

77 ± 14

49 ± 8

 

Age, (year)

70 ± 8

73 ± 8

< 0.001

Age ≥ 75, (%)

30

42

0.011

Female sex, (%)

33

50

< 0.001

Black race, (%)

13

16

0.46

Aspirin use, (%)

52

55

0.56

Statin use, (%)

42

46

0.39

Past or current smoker, (%)

49

44

0.32

SPRINT intensive SBP arm, (%)

55

51

0.44

Systolic blood pressure, (mmHg)

139 ± 14

141 ± 14

0.075

Diastolic blood pressure, (mmHg)

78 ± 10

76 ± 11

0.082

Pulse pressure, (mmHg)

61 ± 13

65 ± 13

0.001

CVD subgroupa, (%)

9

13

0.23

High Framingham risk subgroupb, (%)

89

85

0.15

Urine albumin creatinine ratio, (mg/g)

8 (5, 14)

11 (6, 41)

< 0.001

Fasting LDL cholesterol (mg/dl)

110 ± 30

110 ± 32

0.96

Fasting HDL cholesterol (mg/dl)

55 ± 15

54 ± 15

0.52

  1. Results are presented as proportions (for binary variables) or as mean ± SD (for continuous variables other than ACR) or as median with interquartile range (for ACR)
  2. aCVD subgroup was defined as one or more of MI, ACS, coronary revascularization, carotid revascularization, PAD with revascularization, > 50% stenosis of coronary/carotid/lower extremity artery; or AAA ≥5 mm
  3. bFramingham risk score ≥ 15% for 10 years at SPRINT screening
  4. ceGFR < 60 at SPRINT screening
  5. dEstimated by 4-variable MDRD equation
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BMC Nephrology

ISSN: 1471-2369

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