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Table 2 Determinants of death with functioning graft in univariate analyses

From: Early changes in renal resistive index and mortality in diabetic and nondiabetic kidney transplant recipients: a cohort study

 

HR

p

RI categories (ref = RI < 0.70 both at 1 month & 3 months)

1

 

RI < 0.70 at 1 month & RI ≥ 0.70 at 3 months

2.15 [1.29–3.60]

0.003

RI ≥ 0.70 at 1 month & RI < 0.70 at 3 months

1.90 [1.20–3.03]

0.006

RI ≥ 0.70 at 1 month & RI ≥ 0.70 at 3 months

3.77 [2.71–5.24]

< 0.001

Donor characteristics

 Cardiovascular death

1.59 [1.16–2.16]

0.003

 Donor with diabetes

1.07 [0.54–2.11]

0.850

 Donor gender (Male)

1.01 [0.77–1.33]

0.950

 Donor Age (per 10 year increase)

1.30 [1.20–1.42]

< 0.001

 Donor Age > 60

1.85 [1.44–2.39]

< 0.001

 Cold ischemia (per 1 h increase)

1.01 [0.99–1.02]

0.47

Recipents characteristics at time of transplantation

 Diabetes

3.44 [2.52–4.70]

< 0.001

 NODAT

0.75 [0.66–1.35]

0.75

 Hemodialysis time > 1 year

1.38 [0.98–1.92]

0.059

 Hemodialysis time (per 1 year increase)

1.02 [0.99–1.06]

0.099

 Age (per 10 year increase)

1.92 [1.71–2.16]

< 0.001

 Age > 60 years

3.70 [2.85–4.80]

< 0.001

 Male gender

1.25 [0.95–1.65]

0.110

 BMI > 25

1.68 [1.28–2.20]

< 0.001

 BMI (per 5 pt. increase)

1.35 [1.18–1.54]

< 0.001

Year of transplantation (ref = 1985–1989)

 1990–1999

0.98 [0.59–1.64]

0.940

 2000–2009

1.03 [0.64–1.66]

0.900

 2010–2017

1.42 [0.85–2.40]

0.180

 Double transplantation

2.86 [1.11–7.40]

0.030

 Perfusion machine

2.49 [1.50–4.15]

< 0.001

 DGF

1.38 [1.01–1.89]

0.041

Recipients characteristics at 3 months

 SBP > 140 mmHg

1.67 [1.27–2.18]

< 0.001

 SBP (per 10 mmHg increase)

1.15 [1.07–1.23]

< 0.001

 DBP > 90 mmHg

0.47 [0.24–0.91]

0.026

 PB (per 10 mmHg increase)

0.87 [0.77–0.98]

0.024

 PP > 50 mmHg

2.12 [1.54–2.91]

< 0.001

 PP (per 10 mmHg increase)

1.25 [1.25–1.35]

< 0.001

 eGFR < 45 ml/min

1.39 [1.06–1.82]

0.016

 eGFR MDRD (per 10 ml/min/1.73 m2 increase)

0.89 [0.82–0.96]

0.024

 Tacrolimus

1.18 [0.89–1.57]

0.26

 IL2-R antibodies

1.18 [0.89–1.57]

0.250

Resistive index

 RIM1 (per 0.1 increase)

1.93 [1.65–2.24]

< 0.001

 RIM3 (per 0.1 increase)

2.27 [1.91–2.69]

< 0.001

  1. Values are mean (SD) or absolute (percentage) of patients
  2. NODAT New Onset Diabetes After transplantation, DGF Delayed Graft Function, BMI Body Mass Index, SBP Systolic Blood Pressure, DBP Diastolic Blood Pressure, PP Pulse Pressure, eGFR estimated Glomerular filtration Rate using MDRD formula