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Table 1 Baseline characteristics of study participants by treatment allocation and transplantation during follow-up

From: The probability of receiving a kidney transplantation in end-stage kidney disease patients who are treated with haemodiafiltration or haemodialysis: a pooled individual participant data from four randomised controlled trials

 

HD

HDF

 

No transplantation

Transplantation

p-value**

No transplantation

Transplantation

p-value**

p-value***

N

654

152

 

635

179

  

Age (year)

67.8 (13.1)

54.3 (12.3)

< 0.01

67.4 (13.2)

53.6 (12.3)

< 0.01

0.58

Women

227 (34.7)

59 (38.8)

0.39

219 (34.5)

64 (35.8)

0.82

0.65

History of CVD

284 (43.4)

32 (21.1)

< 0.01

260 (40.9)

35 (19.6)

< 0.01

0.84

Diabetes mellitus

176 (27.5)

24 (16.1)

< 0.01

163 (26.0)

33 (18.4)

0.05

0.68

Dialysis vintage (months)*

27.0 (12.0–55.0)

25.5 (11.8–48.0)

0.23

26.0 (12.0–56.0)

24.0 (12.0–42.0)

0.16

0.69

Systolic BP (mmHg)

141.7 (24.3)

141.6 (21.5)

0.96

141.0 (23.9)

141.6 (21.4)

0.79

0.98

Diastolic BP (mmHg)

72.4 (14.8)

77.0 (11.6)

< 0.01

72.6 (13.5)

78.8 (12.9)

< 0.01

0.18

Vascular access, AVF

520 (79.5)

140 (92.1)

< 0.01

526 (82.8)

160 (89.4)

0.04

0.51

Duration of a dialysis session (min)

230.7 (22.0)

232.1 (20.6)

0.45

230.7 (20.8)

234.2 (21.3)

0.05

0.38

Blood flow (ml/min)*

350 (300–400)

350 (300–400)

0.82

350 (320–400)

350 (300–400)

0.35

0.27

Dialysis single pool Kt/V

1.52 (0.30)

1.53 (0.31)

0.92

1.6 (0.3)

1.5 (0.3)

0.30

0.83

Hemoglobin (g/dL)

11.9 (1.4)

11.9 (1.2)

0.41

11.9 (1.4)

12.2 (1.3)

< 0.01

0.07

Phosphorus (mg/dL)

4.8 (1.5)

5.0 (1.4)

0.14

4.8 (1.5)

5.2 (1.5)

< 0.01

0.08

B-2 microglobulin (mg/L)*

25.9 (19.8–36.2)

28.5 (20.9–38.1)

0.43

25.8 (18.8–34.9)

26.7 (18.7–34.3)

0.88

0.19

BMI after dialysis (kg/m2)

25.4 (4.6)

24.6 (4.0)

0.06

25.1 (5.0)

25.1 (4.0)

0.97

0.25

Albumin (g/dL)

4.0 (0.4)

4.2 (0.4)

< 0.01

4.1 (0.4)

4.2 (0.4)

< 0.01

0.61

C-reactive protein (mg/L)*

5.7 (3.4–12.8)

4.9 (1.6–8.4)

< 0.01

6.2 (3.1–14.1)

4.9 (1.6–9.9)

< 0.01

0.51

Predialysis creatinine (mg/dL)

8.7 (2.7)

9.7 (2.8)

< 0.01

8.4 (2.7)

9.9 (2.7)

< 0.01

0.56

Cholesterol (mmol/L)

3.7 (1.0)

3.7 (1.2)

0.90

3.7 (0.9)

3.6 (0.9)

0.48

0.59

Body Surface Area (m2)

1.8 (0.2)

1.8 (0.2)

0.62

1.8 (0.2)

1.8 (0.2)

0.42

0.96

Convection volume (L)*

–

–

–

22.8 (19.8–25.4)

22.9 (20.0–25.9)

0.40

–

  1. Values are n (%) for categorical variables, and mean (standard deviation) or *median (Q1-Q3) for continuous variables
  2. ** p-values indicates differences between the patients who did not receive transplantation versus those who did in, respectively, the HD and HD arm
  3. *** p-values indicates differences between the patients who received transplantation in the HD arm versus the patients who received transplantation in the HDF arm
  4. CVD cardiovascular disease, BP blood pressure, AVF arteriovenous fistula, BMI body mass index