| Model 1 | Model 2 | Model 3 | |||
---|---|---|---|---|---|---|
Odds ratio (95% CI) | p-value | Odds ratio (95% CI) | p-value | Odds ratio (95% CI) | p-value | |
Age, yrs | 1.07 (1.03–1.13) | <  0.001 | 1.06 (1.01–1.12) | 0.015 | 1.03 (0.94–1.13) | 0.509 |
Men | 4.43 (1.70–11.5) | <  0.001 | 3.38 (1.23–9.32) | 0.019 | 4.73 (0.47–47.5) | 0.186 |
Disease duration, yrs | 1.06 (1.01–1.10) | 0.010 | – | – | 1.08 (0.96–1.22) | 0.180 |
Body mass index, kg/m2 | 0.99 (0.91–1.09) | 0.878 | – | – | 1.05 (0.83–1.32) | 0.684 |
20/(fasting C-peptide × fasting plasma glucose) | 0.99 (0.93–1.06) | 0.596 | – | – | 1.03 (0.82–1.29) | 0.790 |
Creatinine, μmol/L | 1.07 (1.04–1.09) | <  0.001 | – | – | 1.07 (1.02–1.15) | < 0.001 |
Total cholesterol, mmol/L | 0.81 (0.54–1.21) | 0.311 |  |  | 1.05 (0.40–2.74) | 0.921 |
Systolic blood pressure, mmHg | 1.03 (1.01–1.05) | 0.003 | – | – | 1.02 (0.96–1.08) | 0.590 |
Never smoker | 1.00 (Reference) | – | – | – | 1.00 (Reference) | – |
Ex-smoker | 2.90 (1.02–8.22) | 0.045 | – | – | 0.96 (0.11–8.13) | 0.974 |
Current smoker | 3.01 (1.14–7.91) | 0.026 | – | – | 2.54 (0.31–20.6) | 0.381 |
Exercise | 0.76 (0.33–1.76) | 0.527 | – | – | 0.38 (0.07–1.96) | 0.248 |
Total Energy, kcal/day | 1.00 (0.99–1.00) | 0.095 | – | – | 0.99 (0.99–1.00) | 0.431 |
RAS inhibitors | 4.85 (1.98–11.87) | <  0.001 | – | – | 5.04 (0.92–27.6) | 0.062 |
History of CVD | 7.57 (2.02–28.4) | 0.004 |  |  | 1.52 (0.02–99.7) | 0.844 |
Log arachidonic acid | 0.03 (0.01–0.21) | <  0.001 | 0.46 (0.24–0.87) | 0.016 | 0.32 (0.10–0.99) | 0.042 |