Table 1 Patients’ demographics

Median age - years (IQR)

70.3 (11.3)

60.0 (4.8)

70.1 (4.9)

78.9 (5.7)

< 0.001

Gender Male - n (%)

270 (76.7%)

77 (86.5%)

115 (71.0%)

78 (77.2%)

0.02

Median weight - kg (IQR)

80.0 (20.0)

80.0 (24.0)

80.0 (20.0)

75 (17.0)

0.35

Admission year

0.16

 2015

96 (27.3%)

23 (25.8%)

44 (27.2%)

29 (28.7%)

 2016

100 (28.4%)

19 (21.3%)

55 (34.0%)

26 (25.7%)

 2017

119 (33.8%)

38 (42.7%)

50 (30.9%)

31 (30.7%)

 2018

37 (10.5%)

9 (9.0%)

13 (8.0%)

15 (14.9%)

Admission type – n (%)

0.90

 Medical

152 (43.2%)

39 (43.8%)

73 (45.1%)

40 (39.6%)

 Surgical

170 (48.3%)

42 (47.2%)

15 (46.3%)

53 (52.5%)

 Other

30 (8.5%)

8 (9.0%)

14 (8.6%)

8 (7.9%)

Median SAPS Score (IQR)

56 (17)

53 (22)

56 (13)

59 (13)

0.27

Median ICU LOS – days (IQR)

8.6 (16.0)

12.9 (18.8)

8.8 (15.3)

7.7 (14.5)

0.10

Median hospital LOS – days (IQR)

20.0 (35.7)

24.1 (45.0)

18.6 (36.3)

18.0 (31.8)

0.39

Co-existing conditions – n (%)

197 (56.0%)

53 (59.6%)

91 (56.2%)

53 (52.5%)

0.71

 Chronic kidney disease

87 (25.4%)

13 (15.3%)

42 (26.4%)

32 (32.7%)

0.03

 Chronic heart disease

63 (17.9%)

15 (16.9%)

31 (19.1%)

17 (16.8%)

0.83

 Chronic respiratory disease

53 (15.1%)

9 (10.1%)

24 (14.8%)

20 (19.8%)

0.12

 Chronic liver disease

29 (8.2%)

10 (11.2%)

12 (7.4%)

7 (6.9%)

0.50

 Immunosuppression

51 (14.5%)

18 (20.2%)

24 (14.8%)

9 (8.9%)

0.09

 Haematological

31 (8.8%)

10 (11.2%)

14 (8.6%)

7 (6.9%)

0.58

 Metastatic cancer

28 (8.0%)

6 (6.7%)

16 (9.9%)

6 (5.9%)

0.44

 Mechanical ventilation – n (%)

269 (75.9%)

69 (77.5%)

124 (76.5%)

74 (73.3%)

0.76

 Noradrenaline – n (%)

302 (85.8%)

72 (80.9%)

138 (85.2%)

92 (91.1%)

0.05

 Mean max creatinine - mmol/l (SD)

314.1 (204.0)

302.8 (241.6)

324.3 (218.4)

306.9 (134.5)

0.70

 Mean max lactate - mmol/l (SD)

8.4 (5.3)

9.4 (5.7)

8.7 (5.7)

7.2 (4.3)

0.06

Median RRT duration– hours (IQR)

83 (214)

105 (256)

84 (210)

71 (109)

0.17