|
Characteristics
|
Keratoconus
|
Controls
|
IRR (95 % CI)
|
p-value
|
|---|
| |
N
|
CKD
|
PY
|
Ratea
|
N
|
CKD
|
PY
|
Ratea
| | |
|---|
|
All
|
4609
|
48
|
25,491
|
18.83
|
27,654
|
215
|
154,786
|
13.89
|
1.36 (0.99 − 1.86)
|
0.06
|
|
Age (years)
|
|
12 − 19
|
1271
|
3
|
7058
|
4.25
|
7563
|
9
|
43,593
|
2.06
|
2.06 (0.56 − 7.60)
|
0.28
|
|
20 − 29
|
1884
|
10
|
10,742
|
9.31
|
11,377
|
34
|
64,806
|
5.25
|
1.77 (0.88 − 3.59)
|
0.11
|
|
30 − 39
|
898
|
7
|
4717
|
14.84
|
5340
|
24
|
28,102
|
8.54
|
1.74 (0.75 − 4.03)
|
0.20
|
|
≥ 40
|
556
|
28
|
2974
|
94.15
|
3374
|
148
|
18,284
|
80.95
|
1.16 (0.78 − 1.74)
|
0.46
|
|
Gender
|
|
Male
|
2508
|
29
|
14,050
|
20.64
|
14,804
|
90
|
83,605
|
10.76
|
1.92 (1.26 − 2.91)
|
0.002
|
|
Female
|
2101
|
19
|
11,440
|
16.61
|
12,850
|
125
|
71,180
|
17.56
|
0.95 (0.58 − 1.53)
|
0.82
|
|
Comorbidity
|
|
Hypertension
|
148
|
15
|
778
|
192.80
|
868
|
101
|
4385
|
230.33
|
0.84 (0.49 − 1.44)
|
0.52
|
|
Hyperlipidaemia
|
71
|
6
|
323
|
185.76
|
473
|
41
|
2260
|
181.42
|
1.03 (0.44 − 2.41)
|
0.95
|
|
Diabetes mellitus
|
63
|
9
|
322
|
279.50
|
338
|
51
|
1618
|
315.20
|
0.89 (0.44 − 1.80)
|
0.74
|
- Note: The Poisson regression analysis was performed to calculate the incidence rate ratio
- Abbreviations: CI confidence interval, CKD chronic kidney disease, IRR incidence rate ratio, PY person-years
- aRate: per 10,000 person-years
