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Table 2 Risk of chronic kidney disease in the keratoconus group and control group

From: Association between chronic kidney disease and the most common corneal ectasia disease (keratoconus): a nationwide cohort study

Characteristics Keratoconus Controls IRR (95 % CI) p-value
  N CKD PY Ratea N CKD PY Ratea   
All 4609 48 25,491 18.83 27,654 215 154,786 13.89 1.36 (0.99 − 1.86) 0.06
Age (years)
 12 − 19 1271 3 7058 4.25 7563 9 43,593 2.06 2.06 (0.56 − 7.60) 0.28
 20 − 29 1884 10 10,742 9.31 11,377 34 64,806 5.25 1.77 (0.88 − 3.59) 0.11
 30 − 39 898 7 4717 14.84 5340 24 28,102 8.54 1.74 (0.75 − 4.03) 0.20
 ≥ 40 556 28 2974 94.15 3374 148 18,284 80.95 1.16 (0.78 − 1.74) 0.46
Gender
 Male 2508 29 14,050 20.64 14,804 90 83,605 10.76 1.92 (1.26 − 2.91) 0.002
 Female 2101 19 11,440 16.61 12,850 125 71,180 17.56 0.95 (0.58 − 1.53) 0.82
Comorbidity
 Hypertension 148 15 778 192.80 868 101 4385 230.33 0.84 (0.49 − 1.44) 0.52
 Hyperlipidaemia 71 6 323 185.76 473 41 2260 181.42 1.03 (0.44 − 2.41) 0.95
 Diabetes mellitus 63 9 322 279.50 338 51 1618 315.20 0.89 (0.44 − 1.80) 0.74
  1. Note: The Poisson regression analysis was performed to calculate the incidence rate ratio
  2. Abbreviations: CI confidence interval, CKD chronic kidney disease, IRR incidence rate ratio, PY person-years
  3. aRate: per 10,000 person-years