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Table 7 Vasoactive hormones

From: Effect of 0.9% NaCl compared to plasma-lyte on biomarkers of kidney injury, sodium excretion and tubular transport proteins in patients undergoing primary uncemented hip replacement – a randomized trial

Period

Baseline

After surgery

Post-operative day

P-value

(difference in response)

p-AVP (pg/mL)

 PlasmaLyte

0.3 [0.2;0.3]

0.5 [0.3;0.9]*

0.6 [0.4;0.8]*

0.398

 Sodiumchloride

0.3 [0.3;0.4]

0.5 [0.3;1.4]*

0.5 [0.4;0.8]*

p-ANG2 (pg/mL)

 PlasmaLyte

6.5 [3.3;9.0]

5.0 [3.3;8.8]

7.5 [4.3;12.0]*

0.174

 Sodiumchloride

5.5 [3.0;7.5]

4.0 [2.8;5.0]*

6.5 [4.8;8.5]

p-Renin (pg/mL)

 PlasmaLyte

11.2 [6.1;20.9]

9.9 [4.3;22.0]

11.9 [5.2;21.9]

0.540

 Sodiumchloride

5.9 [3.3;7.2]

5.2 [3.2;7.0]*

7.6 [4.9;11.4]*

p-Aldo (pmol/L)

 PlasmaLyte

113 [82;197]

48 [34;85]*

82 [53;142]

0.824

 Sodiumchloride

129 [88;187]

50 [32;106]*

55 [43;96]*

  1. Plasma concentrations arginine vasopressin (p-AVP), angiotensin II (p-AngII), renin (PRC), and aldosterone (p-Aldo). Values are shown as means ± SD or medians with 25 and 75 percentiles in brackets. P-value represents probability of difference in response (response from baseline to infusion) between treatments. Paired t-test or Wilcoxon signed rank test was used to test statistical significant difference from baseline, * = p < 0.05