Table 5 Multivariate time-dependent model for kidney recovery among incident hemodialysis patients
From: Predictors of kidney function recovery among incident ESRD patients
Variables | HR (95% CI) | P-value |
|---|---|---|
Sex (ref = “male”) | ||
Female | 0.96 (0.92,1.00) | 0.050 |
Race (ref = “White”) | ||
Black | 0.49 (0.47,0.52) | < 0.001 |
American Indian/Alaska Native | 0.62 (0.48,0.80) | 0.0003 |
Asian | 0.64 (0.56,0.73) | < 0.001 |
Native Hawaii/Pacific Islander | 0.57 (0.44,0.75) | < 0.001 |
Other | 0.63 (0.39,1.01) | 0.055 |
Age, years (ref = “0–44”) | ||
45–64 | 0.93 (0.86,1.00) | 0.003 |
65+ | 0.74 (0.68,0.80) | < 0.001 |
Primary cause by category (ref = “Diabetes”) | ||
Cystic Kidney | 0.46 (0.35,0.61) | < 0.001 |
Glomerulonephritis | 1.82 (1.68,1.97) | < 0.001 |
Hypertension | 1.12 (1.11,1.25) | < 0.001 |
Missing Cause | 7.41 (4.03,13.62) | < 0.001 |
Other Cause | 3.37 (3.17,3.57) | < 0.001 |
Other Urologic | 1.52 (1.30,1.76) | < 0.001 |
Unknown Cause | 2.02 (1.81,2.26) | < 0.001 |
Comorbidities | ||
Diabetes Mellitus | 0.94 (0.90,0.99) | 0.02 |
Atherosclerotic Heart Disease | 0.97 (0.92,1.03) | 0.28 |
Heart Failure | 1.20 (1.14,1.25) | < 0.001 |
Hypertension | 1.23 (1.17,1.29) | < 0.001 |
Peripheral Vascular Disease | 0.89 (0.83,0.94) | < 0.001 |
COPD | 0.83 (0.79,0.89) | < 0.001 |
Cancer | 1.01 (0.95,1.08) | 0.70 |
Cerebrovascular Disease | 1.07 (1.00,1.15) | 0.04 |
Institutionalized | 0.95 (0.89,1.01) | 0.10 |
Pre-ESRD ESA Use (ref = “no”) | ||
Yes | 0.69 (0.63,0.74) | < 0.001 |
Unknown | 1.06 (1.01,1.12) | 0.03 |
Pre-ESRD Nephrologist care (ref = “no”) | ||
Yes | 0.34 (0.32,0.35) | < 0.0001 |
Unknown | 0.69 (0.64,0.73) | < 0.0001 |
Insurance Coverage (ref = “Medicare only”) | ||
Employer only | 1.06 (0.99,1.15) | 0.12 |
Medicaid only | 0.89 (0.83,0.96) | 0.003 |
Medicare and Medicaid | 0.85 (0.80,0.91) | < 0.001 |
Medicare and employer | 0.99 (0.91,1.08) | 0.86 |
Medicare and other | 1.01 (0.95,1.08) | 0.68 |
None | 0.95 (0.88,1.03) | 0.25 |
Other only | 0.94 (0.86,1.03) | 0.20 |
Laboratory values | ||
Serum Creatinine (per mg/dL) | 1.00 (0.99,1.01) | 0.86 |
eGFR (mL/min/1.73m2) | 1.05 (1.04,1.06) | < 0.001 |
Calcium (per mg/dL) | 1.26 (1.22,1.31) | < 0.001 |
Albumin (per g/dL) | 0.99 (0.95,1.04) | 0.72 |
Phosphorus (per mg/dL) | 0.57 (0.56,0.58) | < 0.001 |
Hemoglobin (per g/dL) | 0.95 (0.93,0.97) | < 0.001 |
Quintile of ultrafiltration rate (ref = ‘1st/lowest’) | ||
2nd | 0.70 (0.67,0.74) | < 0.001 |
3rd | 0.58 (0.55,0.62) | < 0.001 |
4th | 0.50 (0.47,0.53) | < 0.001 |
5th (highest) | 0.41 (0.38,0.43) | < 0.001 |