Fig. 1

Renal pathology of one aMN patient. a, b Optical microscope image demonstrates mesangial cells and matrix proliferation, immune complex deposited in multiple locations (a: periodic acid-silver metheramine, PASM. b: Masson staining, high power field); c The electron micrograph demonstrates the dense deposits in subepithelial, subendothelial, and the basement membrane; Immunofluorescence test: d IgA(++); e IgG(+++); f IgM(++); g C1q(++); h C3(+++); i FRA(+++); j IgG1(+++); k IgG2(++); (not shown)IgG3(-); l IgG4(+++).