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Table 1 Demographics and baseline laboratory values of iMN and aMN patients

From: Renal outcomes of idiopathic and atypical membranous nephropathy in adult Chinese patients: a single center retrospective cohort study

 

iMN group (n = 145)

aMN group (n = 153)

p value

Demographics

 Gender (male %)

78(53.8 %)

89(56.3 %)

0.658

 Age (years old)

56.1 ± 12.2

47.2 ± 16.2

< 0.001

 Prodromic infection(cases)

11(7.6 %)

15(9.5 %)

0.554

 Systolic pressure (mmHg)

132.4 ± 19.0

134.7 ± 18.3

0.121

 Diastolic pressure (mmHg)

81.1 ± 11.4

83.2 ± 10.7

0.089

 Smoking rate (%)

38(26.2 %)

50(31.6 %)

0.298

Laboratory values

 Microscopic hematuria(/uL)

42.0(16.7,105.3)

53.3(21.8,109.1)

0.292

 24hUPE(g/24 h)

5.10(2.79,8.37)

5.50(2.96,8.88)

0.997

 Urea(mmol/L)

5.55 ± 2.35

5.40 ± 2.45

0.589

 Serum creatinine(umol/L)

74.27 ± 26.92

74.74 ± 28.30

0.882

 eGFR(ml/min/1.73m2)

90.59 ± 20.71

97.75 ± 23.83

0.006

 Uric acid(mmol/L)

354.98 ± 99.16

365.99 ± 105.50

0.355

 Albumin(g/L)

27.77 ± 6.38

26.70 ± 7.15

0.173

 Triglyceride (mmol/L)

2.73 ± 2.34

3.04 ± 2.38

0.263

 Cholesterol (mmol/L)

7.69 ± 2.42

7.21 ± 2.43

0.095

 LDL-C (mmol/L)

4.70 ± 1.97

4.44 ± 2.29

0.313

 HDL-C (mmol/L)

1.32 ± 0.45

1.50 ± 2.37

0.393

 Blood IgA(g/L)

2.21 ± 1.04

2.36 ± 1.11

0.225

 Blood IgG(g/L)

7.70 ± 4.14

6.85 ± 2.93

0.047

 Blood IgM(g/L)

1.25 ± 0.71

1.20 ± 0.65

0.601

 Blood C3(g/L)

1.10 ± 0.25

1.07 ± 0.24

0.314

 Blood C4(g/L)

0.28 ± 0.12

0.28 ± 0.11

0.598

 Anti-PLA2R antibody (RU/ml)a

11.0(1.0,58.5)

35.0(1.0,96.0)

0.061

  1. LDL-C low density lipoprotein cholesterol; HDL-C high density lipoprotein cholesterol; 24hUPE 24 h urinary protein excretion. aThe antibody levels of PLA2R were detected in 58 iMN patients and 82 aMN patients