Table 2 The immunofluorescence test of renal biopsy in iMN and aMN patients
Characteristics | iMN group (n = 145) | aMN group (n = 153) | p value |
|---|---|---|---|
Immunofluorescence score, mean/median (range) | |||
IgA | 0.12/0(0,0) | 1.52/2(1,2) | < 0.001 |
IgG | 2.46/2(2,3) | 2.54/3(2,3) | 0.181 |
IgM | 0.70/0(0,2) | 1.49/2(1,2) | < 0.001 |
C1q | 0.15/0(0,0) | 1.59/2(1,2) | < 0.001 |
C3 | 1.82/2(2,2) | 2.18/2(2,3) | < 0.001 |
FRA | 0.31/0(0,0) | 0.62/0(0,2) | 0.004 |
IgG1 | 1.95/2(2,3) | 2.26/2(2,3) | 0.074 |
IgG2 | 0.15/0(0,0) | 1.15/1(0,2) | < 0.001 |
IgG3 | 0.05/0(0,0) | 0.25/0(0,0) | 0.072 |
IgG4 | 2.56/3(2,3) | 2.61/3(2,3) | 0.688 |
Positive patient, n (%) | |||
IgA | 15 (10.3 %) | 126 (82.4 %) | < 0.001 |
IgG | 145 (100 %) | 153 (100 %) | / |
IgM | 60 (41.4 %) | 126 (82.4 %) | < 0.001 |
C1q | 16 (11.0 %) | 133 (86.9 %) | < 0.001 |
C3 | 135 (93.1 %) | 150 (98.0 %) | 0.047 |
FRA | 30 (20.7 %) | 51 (33.3 %) | 0.014 |
IgG1 | 34/39(87.2 %) | 100/102(98.0 %) | 0.018 |
IgG2 | 3/39(7.7 %) | 72/102(70.6 %) | < 0.001 |
IgG3 | 1/39(2.7 %) | 13/102(12.7 %) | 0.112 |
IgG4 | 37/39(94.9 %) | 96/102(94.1 %) | 1.000 |