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Table 4 COX regression of worsening renal function

From: Renal outcomes of idiopathic and atypical membranous nephropathy in adult Chinese patients: a single center retrospective cohort study

 

Worsening of the renal function

 

Univariate COX regression

Multivariate COX regression(model 1)

Multivariate COX regression(model 2)

 

HR

95 % CI

p value

HR

95 % CI

p value

HR

95 % CI

p value

aMN1

0.931

0.515 ~ 1.683

0.813

0.735

0.360 ~ 1.503

0.399

   

Age 1,2

1.019

0.997 ~ 1.041

0.086

1.021

0.976 ~ 1.068

0.365

1.020

0.975 ~ 1.068

0.387

Male gender1,2

1.620

0.852 ~ 3.080

0.141

0.505

0.161 ~ 1.584

0.241

1.986

0.632 ~ 6.240

0.240

Systolic pressure1,2

1.014

0.999 ~ 1.029

0.068

1.011

0.992 ~ 1.029

0.255

1.011

0.992 ~ 1.029

0.251

Diastolic pressure 1,2

1.006

0.980 ~ 1.033

0.644

      

Smoking 1,2

1.900

1.062 ~ 3.397

0.030

1.590

0.715 ~ 3.537

0.256

1.594

0.715 ~ 3.552

0.254

Microscopic hematuria1,2

1.000

0.997 ~ 1.002

0.820

      

Urinary protein excretion at baseline1,2

1.088

1.031 ~ 1.149

0.002

1.090

1.018 ~ 1.167

0.014

1.088

1.013 ~ 1.169

0.021

Serum creatinine1,2

1.009

1.002 ~ 1.017

0.008

1.011

0.983 ~ 1.039

0.448

1.011

0.983 ~ 1.039

0.452

Urea 1,2

1.156

1.056 ~ 1.266

0.002

1.014

0.857 ~ 1.199

0.870

1.014

0.857 ~ 1.200

0.870

eGFR1,2

0.986

0.975 ~ 0.997

0.013

1.017

0.972 ~ 1.064

0.466

1.017

0.972 ~ 1.063

0.473

Uric acid 1,2

1.004

1.002 ~ 1.007

0.001

1.003

1.000 ~ 1.006

0.077

1.003

1.000 ~ 1.006

0.077

Cholesterol1,2

1.030

0.913 ~ 1.161

0.635

      

Triglyceride 1,2

1.039

0.946 ~ 1.142

0.421

      

LDL-C1,2

0.943

0.818 ~ 1.087

0.421

      

HDL-C 1,2

0.650

0.305 ~ 1.386

0.265

      

Albumin 1,2

0.975

0.921 ~ 1.031

0.371

      

Anti-PLA2R antibody concentration1,2

0.995

0.988 ~ 1.003

0.202

      

Proteinuria non-remission at 6th month1

4.016

2.009 ~ 8.028

< 0.001

3.571

1.741 ~ 7.325

0.001

   

Proteinuria remission at 6th month of iMN2,a

/

 

0.002

/

  

/

 

0.005

Proteinuria non-remission at 6th month of iMN2

3.333

1.399 ~ 7.945

0.007

   

4.248

1.485 ~ 12.151

0.007

Proteinuria remission at 6th month of aMN2

0.538

0.144 ~ 2.088

0.356

   

0.675

0.155 ~ 2.942

0.601

Proteinuria non-remission at 6th month of aMN2

3.210

1.362 ~ 7.565

0.008

   

3.194

1.094 ~ 9.324

0.034

  1. 1: included in Model 1, 2: included in Model 2,aAs a reference