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Table 1 Participant demographics and clinical characteristics

From: Differences in physical symptoms between those with and without kidney disease: a comparative study across disease stages in a UK population

 

Non-KD reference

Non-dialysis kidney disease

HD

PD

KTRs

Stage 1–2

Stage 3

Stage 4

Stage 5ND

N = 853

N = 72

N = 182

N = 194

N = 82

N = 630

N = 28

N = 230

Age (years)

46.6 (16.1)

46.0 (16.2)

64.2 (14.9)

70.7 (15.1)

66.0 (18.0)

63.0 (14.6)

55.1 (18.2)

51.8 (13.5)

Sex (male n, %)

232 (27%)

36 (50%)

99 (54%)

105 (54%)

57 (63%)

395 (63%)

17 (61%)

143 (62%)

Ethnicity

White British (n, %)

607 (72%)

55 (78%)

162 (90%)

175 (91%)

73 (81%)

391 (63%)

17 (63%)

181 (79%)

South Asian (n, %)

96 (11%)

8 (11%)

7 (4%)

12 (6%)

7 (8%)

91 (15%)

6 (22%)

24 (11%)

Other (n, %)

137 (16%)

8 (11%)

12 (7%)

6 (3%)

10 (11%)

140 (23%)

4 (15%)

24 (11%)

eGFR (ml/min/1.73m2)

a

77.6 (11.7)

41.0 (7.9)

22.7 (4.1)

11.8 (2.8)

46.8 (22.0)

CRP (mg/L)

a

10.4 (23.5)

11.0 (19.4)

18.4 (56.1)

11.6 (16.0)

18.9 (34.5)

22.3 (39.5)

13.9 (32.4)

Haemoglobin (g/dL)

a

136.8 (157.5)

88.0 (55.9)

93.8 (47.6)

98.8 (34.6)

103.4 (40.5)

101.8 (21.9)

100.5 (48.2)

Albumin (g/dL)

a

41.7 (4.1)

41.0 (6.3)

40.9 (4.5)

40.1 (5.6)

38.6 (5.0)

36.2 (5.7)

42.1 (5.9)

HbA1C (%)

a

5.7 (0.9)

6.9 (1.6)

6.8 (1.5)

6.8 (1.9)

6.5 (1.6)

6.8 (1.6)

6.0 (1.3)

Dialysis vintage (mths)

a

b

b

b

b

40.8 (46.0)

12.3 (20.7)

Transplant vintage (mths)

a

b

b

b

b

b

b

67.5 (80.6)

Kt/V (ratio)

a

b

b

b

b

1.81 (5.85)

a

b

URR (%)

a

b

b

b

b

99.5 (451.3)

a

b

No. of comorbidities

1.2 (1.4)

1.6 (1.7)

3.5 (2.8)

4.6 (2.6)

4.2 (2.0)

2.5 (1.7)

3.2 (1.9)

2.7 (2.1)

Hypertension (n, %)

a

27 (28%)

121 (67%)

144 (74%)

63 (70%)

409 (65%)

20 (71%)

141 (61%)

Other CVD (n, %)

66 (8%)

7 (10%)

46 (25%)

73 (38%)

29 (35%)

243 (39%)

5 (18%)

29 (13%)

Diabetes (n, %)

35 (4%)

6 (8%)

47 (26%)

81 (41%)

36 (40%)

261 (41%)

12 (43%)

53 (23%)

MSK problems (n, %)

233 (27%)

7 (10%)

44 (24%)

55 (28%)

20 (22%)

70 (11%)

11 (39%)

45 (20%)

Respiratory conditions (n, %)

109 (13%)

6 (8%)

23 (13%)

27 (14%)

10 (11%)

64 (10%)

2 (7%)

15 (7%)

  1. Data shown as mean and standard deviation, unless otherwise stated. Frequencies reported as number and valid percentage. KD Kidney disease, ND Non-dialysis, HD Haemodialysis, PD Peritoneal dialysis, KTRs Kidney transplant recipients, eGFR Estimated glomerular filtration rate, CRP C-reactive protein, URR Urea reduction ratio. a = not measured; b = not applicable to group. Other CVD includes heart disease and stroke; respiratory conditions include chronic obstructive pulmonary disorder and asthma