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Table 2 Association of rs35767 genotype with BP according to sex

From: Association between polymorphism at IGF-1 rs35767 gene locus and long-term decline in renal function: a Japanese retrospective longitudinal cohort study

 

SBP

DBP

MBP

Model

1(M)

2(F)

3(All)

1(M)

2(F)

3(All)

1(M)

2(F)

3(All)

 

β

(SE)

p

β

(SE)

p

β

(SE)

p

β

(SE)

p

β

(SE)

p

β

(SE)

p

β

(SE)

p

β

(SE)

p

β

(SE)

p

CC

Ref

 

Ref

 

Ref

 

Ref

 

Ref

 

Ref

 

Ref

 

Ref

 

Ref

 

TC

0.89 (0.92)

0.33

0.55 (1.91)

0.77

1.06 (0.84)

0.20

0.24 (0.60)

0.38

− 0.97 (1.61)

0.55

0.91 (0.56)

0.10

1.12 (0.64)

0.08

−0.46 (1.57)

0.41

0.96 (0.59)

0.10

TT

0.60 (1.44)

0.68

−5.96 (2.95)

<0.05

−0.02 (1.32)

0.99

0.69 (0.94)

0.46

−5.61 (2.50)

< 0.05

−0.21 (0.88)

0.81

0.66 (1.01)

0.51

−5.72 (2.43)

< 0.05

−0.14 (0.94)

0.88

  1. Model 1, males only (M); Model 2, females only (F); Model 3, males and females (All); all models adjusted for age, BMI, eGFR, UA, LDLC, HbA1c
  2. n = 1506 (F/M, 206/1300)
  3. SBP systolic blood pressure, DBP diastolic blood pressure, MBP mean blood pressure, BMI body mass index, eGFR estimated glomerular filtration rate, UA uric acid, LDLC low-density lipoprotein cholesterol, HbA1c glycated hemoglobin, β regression coefficients, ref. reference, SE standard error
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BMC Nephrology

ISSN: 1471-2369

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