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Table 2 Association of rs35767 genotype with BP according to sex

From: Association between polymorphism at IGF-1 rs35767 gene locus and long-term decline in renal function: a Japanese retrospective longitudinal cohort study

  SBP DBP MBP
Model 1(M) 2(F) 3(All) 1(M) 2(F) 3(All) 1(M) 2(F) 3(All)
  β
(SE)
p β
(SE)
p β
(SE)
p β
(SE)
p β
(SE)
p β
(SE)
p β
(SE)
p β
(SE)
p β
(SE)
p
CC Ref   Ref   Ref   Ref   Ref   Ref   Ref   Ref   Ref  
TC 0.89 (0.92) 0.33 0.55 (1.91) 0.77 1.06 (0.84) 0.20 0.24 (0.60) 0.38 − 0.97 (1.61) 0.55 0.91 (0.56) 0.10 1.12 (0.64) 0.08 −0.46 (1.57) 0.41 0.96 (0.59) 0.10
TT 0.60 (1.44) 0.68 −5.96 (2.95) <0.05 −0.02 (1.32) 0.99 0.69 (0.94) 0.46 −5.61 (2.50) < 0.05 −0.21 (0.88) 0.81 0.66 (1.01) 0.51 −5.72 (2.43) < 0.05 −0.14 (0.94) 0.88
  1. Model 1, males only (M); Model 2, females only (F); Model 3, males and females (All); all models adjusted for age, BMI, eGFR, UA, LDLC, HbA1c
  2. n = 1506 (F/M, 206/1300)
  3. SBP systolic blood pressure, DBP diastolic blood pressure, MBP mean blood pressure, BMI body mass index, eGFR estimated glomerular filtration rate, UA uric acid, LDLC low-density lipoprotein cholesterol, HbA1c glycated hemoglobin, β regression coefficients, ref. reference, SE standard error