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Table 1 Preoperative patient characteristics and 24-hours urine metabolic profile

From: Excretion of urine extracellular vesicles bearing markers of activated immune cells and calcium/phosphorus physiology differ between calcium kidney stone formers and non-stone formers

Variables

NSF

(n = 21)

High RP CSF (n = 8)

Low RP CSF (n = 16)

CSF

(High + Low RP), (n = 24)

Age (years)

65.5

(57.4, 73.0)

69.2

(60.4, 72.2)

61.2

(50.1, 72.9)

63.9

(57.1, 72.2)

Sex n (%)

Male

10 (47.6 %)

7 (87.5 %)

8 (50 %)

15 (62.5 %)

Female

11 (52.4 %)

1 (12.5 %)

8 (50 %)

9 (37.5 %)

Body mass index (kg/m2)

26.2

(24.5, 30.5)

30.5

(24.3, 34.9)

27.7

(24.4, 30.0)

28.7

(24.4, 32.4)

Systolic Blood Pressure (mmHg)

124

(116.0, 137.5)

130.5

(112.3, 133.5)

119

(114, 137.8)

126

(114, 136.8)

Diastolic Blood Pressure (mmHg)

72

(64.0, 82.0)

72

(62.0, 82.3)

69.5

(62.0, 77.0)

70

(62.0, 77.8)

Urine pH

6.4

(6.0, 7.0)

5.5 a

(5.2, 5.6)

6.2 b

(5.7, 6.5)

6.0 c

(5.4, 6.3)

Urine calcium (mg/24hr)

158.3

(86.4, 192.3)

255.5 a

(132.5, 406.0)

186.5

(103.2, 273.2)

207.5 c

(110.8, 330.0)

Urine oxalate (mmol/24hr)

0.27

(0.22, 0.35)

0.41 a,b

(0.28, 0.64)

0.28

(0.22, 0.36)

0.30 c

(0.25, 0.48)

Urine chloride (mmol/24hr)

113.8

(73.4, 139.7)

170.5 a

(121.8, 233.3)

107 b

(78.0, 153.8)

117.8

(99.6, 189.3)

Urine citrate (mg/24hr)

625.3

(331.3, 756.8)

298.5

(206.3, 805.1)

557

(231.7, 690.5)

450.2

(218.8, 690.5)

Urine creatinine (mg/24hr)

869.2

(633.1, 1067.3)

1790.5 a

(1583, 2060)

1068 b

(844.3, 1451.5)

1384.1 c

(904.8, 1647.3)

Urine osmolality (mOsm/kg)

458

(314.5, 731.5)

494

(126.3, 687)

363

(319.5, 472.8)

392.5

(319.5, 556.8)

Urine phosphorus (mg/24hr)

516.3

(371.5, 759.9)

1204.5 a

(1030, 1575.3)

747.8 b

(483.1, 1008.3)

913.5 c

(525.3, 1169.6)

Urine potassium (mmol/24hr)

48.7

(36.7, 76.0)

80.5

(59.3, 86.8)

45.4

(33.1, 66.8)b

59.5

(36.4, 78.8)

Urine sodium (mmol/24hr)

116.3

(72.1, 155.1)

174 a

(131.5, 257.5)

118.5 b

(91, 191.8)

144.5

(106.3, 215.7)

Urine sulfate (mmol/24hr)

15.4

(11.3, 27.5)

25

(12, 34)

11

(9, 24)

21.5

(10.3, 27.3)

Urine volume (ml, 24 h)

2087

(1597, 2529)

2388

(1596, 3222)

2095

(1454, 2788)

2115

(1454, 3064)

Urine calcium phosphate-brushite SS (DG)

−0.8

(− 1.7, 0.4)

-1.7

(-2.0, 0.1)

-0.1

(-1.7, 0.8)

-0.34

(-2.0, 0.6)

Urine calcium oxalate SS (DG)

1.1

(0.7, 1.6)

1.8

(1.2. 2.5)

1.6

(1.1, 2.3)

1.6 c

(1.1, 2.3)

  1. Data are presented as median (25th and 75th percentile)
  2. P values in bold denote significance at < 0.05 level
  3. Abbreviations: CSF calcium stone formers; DG delta Gibbs; NSF non-stone formers; SS supersaturation
  4. aSignificant difference between high RP CSF and NSFs
  5. bSignificant difference between high RP and low RP CSF
  6. cSignificant difference between CSFs and NSFs