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Table 2 Comparison of clinical features and pregnancy outcomes between HDP-related and non-HDP Pr-AKI patients

From: Pregnancy-related acute kidney injury at high altitude: a retrospective observational study in a single center

Variables

HDP-related

N = 48 (50 fetuses)

Non-HDP

N = 50 (50 fetuses)

P value

Age (years)

28.3 ± 5.1

26.9 ± 6.0

0.255

SBP (mmHg)

154.3 ± 19.0

110.6 ± 13.5

< 0.001

DBP (mmHg)

101.4 ± 15.3

69.3 ± 10.1

< 0.001

Serum ALB (g/L)

24.9 ± 5.6

27.5 ± 5.3

0.020

SCr (umol/L)

86(77–98)

90(78–111)

0.355a

Serum UA (umol/L)

477.1 ± 82.8

406.2 ± 115.7

0.001

Maternal death (n%)

2(4.0 %)

2(3.7 %)

1.000b

Gestational age at delivery

(in weeks)

37.1 ± 2.8

37.0 ± 4.0

0.858

Delivery via cesarean section (n%)

27(56.3 %)

15(31.3 %)

0.014

Pre-term birth (n%)

17(35.4 %)

12(26.1 %)

0.328

Stillbirth/neonatal death (n%)

6(13.6 %)

10(21.3 %)

0.339

Neonatal weight (g)

2770.2 ± 647.4

3023.8 ± 523.7

0.054

Apgar score at 1 min

7.8 ± 3.3

7.7 ± 3.7

0.923

IUGR (n%)

11(25.0 %)

1(2.3 %)

0.003b

Admission to NICU (n%)

11(22.0 %)

3(6.5 %)

0.019b

LBWI (n%)

17(37.8 %)

7(15.9 %)

0.020

Renal recovery on discharge (n%)

29(76.3 %)

35(85.4 %)

0.305

  1. AKI acute kidney injury; HDP hypertensive disorders of pregnancy; SBP systolic blood pressure; DBP diastolic blood pressure; ALB albumin; SCr serum creatinine; UA uric acid; IUGR intrauterine growth restriction; LBWI low birth weight infant; NICU neonatal intensive care unit
  2. Values for categorical variables were given as number (percentage); values for continuous variables were given as mean ± standard deviation or median (interquartile range)
  3. P < 0.05 was considered to be statistically significant
  4. a: Wilcoxon 2-sample tests
  5. b: Fisher exact test