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Table 4 Receiver operating characteristic curve analysis

From: Presepsin and prognostic nutritional index are predictors of septic acute kidney injury, renal replacement therapy initiation in sepsis patients, and prognosis in septic acute kidney injury patients: a pilot study

Variable

AUC

Cut-off

P value

Sensitivity

Specificity

28-day mortality

 Presepsin on Day 1 (pg/mL)

0.77

1373.00

0.004

0.82

0.77

 Presepsin on Day 2 (pg/mL)

0.83

1581.00

0.000

0.86

0.68

 Presepsin on Day 3 (pg/mL)

0.91

1819.00

0.000

1.00

0.82

 Presepsin on Day 5 (pg/mL)

1.00

3014.00

0.000

1.00

1.00

 ΔPresepsin Day 2 - Day 1 (pg/mL)

0.76

507.00

0.059

0.71

0.86

 ΔPresepsin Day 3 - Day 1 (pg/mL)

0.91

−10.00

0.000

1.00

0.76

 ΔPresepsin Day 5 - Day 1 (pg/mL)

0.79

2385.00

0.176

0.75

1.00

 iPS-PLR

0.75

1.00

0.002

0.91

0.46

60-day mortality

 Presepsin on Day 1 (pg/mL)

0.70

1373.00

0.063

0.75

0.76

 Presepsin on Day 2 (pg/mL)

0.73

1581.00

0.052

0.75

0.67

 Presepsin on Day 3 (pg/mL)

0.75

1819.00

0.134

0.80

0.81

 Presepsin on Day 5 (pg/mL)

0.80

3014.00

0.134

0.80

1.00

 ΔPresepsin Day 2 - Day 1 (pg/mL)

0.74

507.00

0.045

0.63

0.86

 ΔPresepsin Day 3 - Day 1 (pg/mL)

0.85

−10.00

0.000

0.80

0.75

 ΔPresepsin Day 5 - Day 1 (pg/mL)

0.72

2385.00

0.238

0.60

1.00

 iPS-PLR

0.70

1.00

0.024

0.83

0.44

90-day mortality

 Presepsin on Day 1 (pg/mL)

0.65

1373.00

0.142

0.64

0.74

 Presepsin on Day 2 (pg/mL)

0.65

1581.00

0.190

0.60

0.63

 Presepsin on Day 3 (pg/mL)

0.74

1545.00

0.085

0.83

0.73

 Presepsin on Day 5 (pg/mL)

0.79

1399.00

0.082

0.83

0.73

 ΔPresepsin Day 2 - Day 1 (pg/mL)

0.69

507.00

0.092

0.50

0.84

 ΔPresepsin Day 3 - Day 1 (pg/mL)

0.87

−10.00

0.000

0.83

0.80

 ΔPresepsin Day 5 - Day 1 (pg/mL)

0.74

244.00

0.108

0.67

0.82

180-day mortality

 Presepsin on Day 1 (pg/mL)

0.65

1336.00

0.121

0.67

0.68

 Presepsin on Day 2 (pg/mL)

0.68

1581.00

0.093

0.64

0.67

 Presepsin on Day 3 (pg/mL)

0.80

1545.00

0.019

0.86

0.79

 Presepsin on Day 5 (pg/mL)

0.77

1313.00

0.063

0.86

0.70

 ΔPresepsin Day 2 - Day 1 (pg/mL)

0.73

507.00

0.022

0.55

0.89

 ΔPresepsin Day 3 - Day 1 (pg/mL)

0.91

−10.00

0.000

0.86

0.86

 ΔPresepsin Day 5 - Day 1 (pg/mL)

0.76

−23.00

0.051

0.71

0.80

  1. AUC area under the curve, iPS inflammation-presepsin score, PLR platelet to lymphocyte ratio