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Fig. 1 | BMC Nephrology

Fig. 1

From: Membranous nephropathy associated with multicentric Castleman’s disease that was successfully treated with tocilizumab: a case report and review of the literature

Fig. 1

Light microscopy. a A submental lymph node biopsy showed diffuse interfollicular plasma cell infiltration (Hematoxylin and eosin staining [HE]). Left panel: Bar = 50 μm, Right panel: Bar = 50 μm. b Skin biopsy showed plasma cells in the perivascular area (HE). Left panel: Bar = 250 μm, Right panel: Bar = 100 μm. c Kidney biopsy findings. HE staining showed no sign of inflammatory cell infiltration in the glomeruli. Periodic acid Schiff (PAS) staining showed no signs of mesangial proliferation, crescents, or adhesion. Periodic acid methenamine silver (PAM) staining showed the appearance of bubbling (enlarged rectangle) in the glomerular basement membranes. Masson-Trichrome (MT) staining showed no sign of immune complex deposits in the glomeruli. Bars = 50 μm

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BMC Nephrology

ISSN: 1471-2369

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