Fig. 2

Comparison of renal survival between IgAN patients of positive- and negative- family history subgroups. Renal survival is analyzed using the log- rank scale test and compared between the two subgroups of IgAN patients, i.e., those with a positive- or negative-FH. A A hard endpoint of ESRD (eGFR less than 15 mL/min/1.73 m²) was used. B The combined renal outcomes, consisting of both the hard endpoint (eGFR< 15 mL/min/1.73 m²) and surrogate endpoint (a 50% or more reduction in renal function), were used. IgAN, IgA nephropathy; FH, familial history of renal diseases; ESRD, end-stage renal disease; eGFR, estimated glomerular filtration rate