Table 1 Comparison of selected variables of patients undergoing either simultaneous heart-kidney or solitary kidney transplantation
Variables | HKTx | KTx | p-value | ||||||
|---|---|---|---|---|---|---|---|---|---|
Mean; Median (Range) | N (%) | M. v. | Mean; Median (Range) | N (%) | M. v. | ||||
Recipient data | Age (in years) | 52.52; 54 (35-65) | 0 (0) | 55.67; 58 (34-70) | 0 (0) | 0.222 | |||
Male gender | 17 (63.0) | 18 (66.7) | 0.776 | ||||||
Height (in cm) | 174.63; 173 (160-192) | 171.63; 172 (156-184) | 0.166 | ||||||
Weight (in kg) | 74.57; 72 (44-106) | 73.01; 72.5 (44-103) | 0.769 | ||||||
BMI (in kg/m2) | 24.29; 24.77 (15.59-31.44) | 24.68; 24.92 (17.70-32.00) | 0.711 | ||||||
Cause of renal failure | Nephritis | 8 (29.6) | 11 (40.7) | n.a. | |||||
Hypertension | 3 (11.1) | 1 (3.7) | |||||||
CNI toxicity | 3 (11.1) | 0 (0) | |||||||
Cystic kidney disease | 3 (11.1) | 1 (3.7) | |||||||
Diabetes | 3 (11.1) | 3 (11.1) | |||||||
Focal segmental glomerulosclerosis | 1 (3.7) | 2 (7.4) | |||||||
Cardiorenal syndrom | 3 (11.1) | 0 (0) | |||||||
Others | 2 (7.4) | 8 (29.6) | |||||||
Undefined | 1 (3.7) | 1 (3.7) | |||||||
Cause of cardiac failure | Dilated CM | 15 (55.6) | n.a. | n.a. | |||||
Ischemic CM | 8 (29.6) | ||||||||
Others/Uncertain | 4 (14.8) | ||||||||
Number of cardiovascular risk factors | 1.26; 1 (0-5) | 1.93; 2 (1-3) | 0.004 | ||||||
Previous HTx | 3 (11.1) | 0 (0) | 0.105 | ||||||
Previous KTx | 1 (3.7) | 2 (7.4) | 0.549 | ||||||
Previous cardiac operation requiring sternotomy | 12 (44.4) | n.a. | n.a. | ||||||
Prior dialysis | 18 (66.7) | 27 (100) | <0.001 | ||||||
Time on dialysis (in months) | 20.22; 9 (0-66) | 85.85; 86 (12-190) | <0.001 | ||||||
GFR prior Tx for patients without prior dialysis (in ml/min) | 22.67; 21 (15-35) | n.a. | n.a. | ||||||
PRA prior Tx (in %) | 4.89; 0 (0-59) | 2.04; 0 (0-55) | 0.052 | ||||||
Highest PRA (in %) | 7.70; 0 (0-59) | 5.00; 0 (0-88) | 0.453 | ||||||
Donor data | Age (in years) | 41.56; 47 (16-59) | 43.41; 49 (18-62) | 0.550 | |||||
Male gender | 21 (77.8) | 20 (74.1) | 0.750 | ||||||
Height (in cm) | 175.85; 175 (165-190) | 176.71; 176.5 (160-190) | 3 (11.1) | 0.688 | |||||
Weight (in kg) | 80.22; 78 (60-120) | 79.17; 75 (61-110) | 0.740 | ||||||
BMI (in kg/m2) | 25.87; 24.84 (21.91-35.92) | 25.34; 24.69 (20.88-32.65) | 0.491 | ||||||
Creatinine (in μmol/l) | 72.12; 67.5 (35-181) | 1 (3.7) | 123.37; 80 (31-725) | 0 (0) | 0.071 | ||||
ICU ventilation (in days) | 4.85; 3.5 (1-18) | 4.85; 4 (1-15) | 0.634 | ||||||
Surgical details | Number of HLA mismatches | 4.15; 4 (2-6) | 0 (0) | 3.70; 4 (2-5) | 0.159 | ||||
Operation time (in min) | 116.78; 101.00 (60-225) | 136.70; 134 (67-205) | 0.022 | ||||||
Cold ischemia time KTx (in min) | 973.63; 900 (255-2084) | 1125.74; 1118 (308-2286) | 0.269 | ||||||
PRBC (yes) | 18 (66.7) | 1 (3.7) | 2 (7.4) | <0.001 | |||||
Number of PRBC | 1.89; 2 (1-4) | 1.50; 1.5 (1-2) | <0.001 | ||||||
FFP (yes) | 13 (48.1) | 1 (3.7) | <0.001 | ||||||
Number of FFP | 3.23; 3 (1-9) | 5.00; 5 (5-5) | <0.001 | ||||||