Table 2 Comparison of variables of patients undergoing either simultaneous heart-kidney transplantation with prior cardiac surgery or solitary kidney transplantation
Variables | HKTx with prior cardiac surgery | KTx | p-value | ||||||
|---|---|---|---|---|---|---|---|---|---|
Mean; Median (Range) | N (%) | M. v. | Mean; Median (Range) | N (%) | M. v. | ||||
Recipient data | Age (in years) | 52.83; 55.5 (37-63) | 0 (0) | 55.67; 58 (34-70) | 0 (0) | 0.399 | |||
Male gender | 9 (75.0) | 18 (66.7) | 0.719 | ||||||
Height (in cm) | 178.17; 177.5 (172-192) | 171.63; 172 (156-184) | 0.015 | ||||||
Weight (in kg) | 80.58; 74.75 (60-106) | 73.01; 72.5 (44-103) | 0.127 | ||||||
BMI (in kg/m2) | 25.31; 24.42 (20.28-30.64) | 24.68; 24.92 (17.70-32.00) | 0.628 | ||||||
Cause of renal failure | Nephritis | 3 (25.0) | 11 (40.7) | n.a. | |||||
Hypertension | 1 (8.3) | 1 (3.7) | |||||||
CNI toxicity | 3 (25.0) | 0 (0) | |||||||
Cystic kidney disease | 1 (8.3) | 1 (3.7) | |||||||
Diabetes | 0 (0) | 3 (11.1) | |||||||
Focal segmental glomerulosclerosis | 1 (8.3) | 2 (7.4) | |||||||
Cardiorenal syndrom | 2 (16.7) | 0 (0) | |||||||
Others | 0 (0) | 8 (29.6) | |||||||
Undefined | 1 (8.3) | 1 (3.7) | |||||||
Cause of cardiac failure | Dilated CM | 4 (33.3) | n.a. | n.a. | |||||
Ischemic CM | 5 (41.7) | ||||||||
Others/Uncertain | 3 (25.0) | ||||||||
Number of cardiovascular risk factors | 1.58; 1 (0-3) | 1.93; 2 (1-3) | 0.210 | ||||||
Previous HTx | 3 (25.0) | 0 (0) | 0.024 | ||||||
Previous KTx | 0 (0) | 2 (7.4) | 1.000 | ||||||
Prior dialysis | 5 (41.7) | 27 (100) | <0.001 | ||||||
Time on dialysis (in months) | 11.23; 0 (0-57) | 85.85; 86 (12-190) | <0.001 | ||||||
GFR prior Tx for patients without prior dialysis (in ml/min) | 20.57; 20 (15-27) | n.a. | n.a. | ||||||
PRA prior Tx (in %) | 10.25; 0 (0-59) | 2.04; 0 (0-55) | 0.014 | ||||||
Highest PRA (in %) | 11.50; 0 (0-59) | 5.00; 0 (0-88) | 0.180 | ||||||
Donor data | Age (in years) | 42.08; 45.5 (19-57) | 43.41; 49 (18-62) | 0.642 | |||||
Male gender | 11 (91.7) | 20 (74.1) | 0.394 | ||||||
Height (in cm) | 179.00; 180.0 (170-190) | 176.71; 176.5 (160-190) | 3 (11.1) | 0.377 | |||||
Weight (in kg) | 83.33; 80.0 (65-120) | 79.17; 75 (61-110) | 0.398 | ||||||
BMI (in kg/m2) | 25.94; 24.76 (21.91-35.92) | 25.34; 24.69 (20.88-32.65) | 0.655 | ||||||
Creatinine (in μmol/l) | 79.17; 71 (43-181) | 123.37; 80 (31-725) | 0 (0) | 0.425 | |||||
ICU ventilation (in days) | 4.33; 2 (1-18) | 4.85; 4 (1-15) | 0.271 | ||||||
Surgical details | Number of HLA mismatches | 4.00; 4 (3-6) | 3.70; 4 (2-5) | 0.447 | |||||
Operation time (in min) | 136.70; 134 (67-205) | 139.75; 134 (85-225) | 0.820 | ||||||
Cold ischemia time KTx (in min) | 1161.50; 1224.5 (657-2084) | 1125.74; 1118 (308-2286) | 0.845 | ||||||
PRBC (yes) | 8 (66.7) | 2 (7.4) | <0.001 | ||||||
Number of PRBC | 1.88; 2 (1-3) | 1.50; 1.5 (1-2) | 0.002 | ||||||
FFP (yes) | 7 (58.3) | 1 (3.7) | <0.001 | ||||||
Number of FFP | 4.00; 4 (2-9) | 5.00; 5 (5-5) | 0.008 | ||||||