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Table 4 Comparison of graft and patient outcome after either simultaneous heart-kidney with prior cardiac surgery or solitary kidney transplantation

From: Simultaneous heart-kidney transplantation results in respectable long-term outcome but a high rate of early kidney graft loss in high-risk recipients – a European single center analysis

Variables

HKTx with prior cardiac surgery

KTx

p-value

Mean; Median (Range)

N (%)

M. v.

Mean; Median (Range)

N (%)

M. v.

Outcome

1-month eGFR (in ml/min)

67.03; 69,47 (37.34-93.19)

 

6 (50.0)

44.23; 42.07 (10.23-92.15)

 

1 (3.7)

0.019

3-month eGFR (in ml/min)

51.16; 52.30 (23.07-72.63)

 

5 (41.7)

46.60; 44.83 (19.44-97.48)

 

2 (7.4)

0.622

6-month eGFR (in ml/min)

49.32; 41.81 (18.81-91.41)

 

4 (33.3)

49.38; 42.22 (16.38-105.52)

 

2 (7.4)

0.995

1-year eGFR (in ml/min)

49.18; 47.72 (13.6-79.08)

 

4 (33.3)

51.53; 49.09 (21.25-80.24)

 

3 (11.1)

0.773

2-year eGFR (in ml/min)

48.27; 46.18 (24.84-69.80)

 

5 (41.7)

49.44; 47.22 (22.13-77.70)

 

4 (14.8)

0.877

3-year eGFR (in ml/min)

46.84; 36.16 (13.81-85.31)

 

5 (41.7)

47.34; 47.79 (27.29-78.49)

 

3 (11.1)

0.951

5-year eGFR (in ml/min)

43.10; 30.99 (19.92-73.83)

 

7 (58.3)

47.82; 43.15 (21.28-90.58)

 

5 (18.5)

0.620

10-year eGFR (in ml/min)

45.88; 53.81 (15.98-67.86)

 

9 (75.0)

49.18; 41.46 (30.13-88.25)

 

16 (59.3)

0.817

Subsequent dialysis

 

6 (50.0)

0 (0)

 

6 (22.2)

0 (0)

0.133

ICU stay (in days)

11.33; 8.5 (1-36)

 

2.07; 1 (0-8)

 

<0.001

Hospital stay (in days)

62.50; 28 (14-236)

 

21.59; 20 (8-56)

 

0.012

Surgical complications

 

7 (58.3)

 

4 (14.8)

0.017

Primary nonfunction (renal graft)

 

4 (33.3)

 

0 (0)

0.006

In-hospital mortality

 

3 (25.0)

 

0 (0)

0.024

  1. HKTx: simultaneous heart and kidney transplantation; KTx: kidney transplantation; HTx: heart transplantation; eGFR: estimated glomerular filtration rate; ICU: intensive care unit; M.v.: missing values. Bold values indicate statistical significance.