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Table 1 Cohort Demographics and Covariates by Presence of Antihypertensive PIM Refill after Dialysis Initiation in the Sub-Cohort

From: Risks associated with continuation of potentially inappropriate antihypertensive medications in older adults receiving hemodialysis

 

Total (n = 5981)

Continued (n = 3920)

Discontinued (n = 2061)

p-value

Age at first ESRD service

   

<0.001

 Mean (SD)

76 (6)

75 (6)

76 (7)

 

Female

3077 (51%)

2011 (51%)

1066 (52%)

0.75

Race/Ethnicity

   

<0.001

 Non-Hispanic white

3450 (58%)

2164 (55%)

1286 (62%)

 

 Non-Hispanic black

1469 (25%)

1031 (26%)

438 (21%)

 

 Hispanic

703 (12%)

488 (12%)

215 (10%)

 

 Other

354 (6%)

237 (6%)

117 (6%)

 

Medicare/Medicaid Dual Eligible status

1795 (30%)

1233 (31%)

562 (27%)

0.001

Comorbidity Index

   

<0.001

 Mean (SD)

8.0 (4.1)

7.6 (4.1)

8.8 (4.0)

 

 Median (IQR)

8.0 (5.0, 11.0)

8.0 (4.0, 11.0)

9.0 (6.0, 12.0)

 

Diabetes

4560 (76%)

3001 (77%)

1559 (75%)

0.43

Medication count

   

<0.001

 Mean (SD)

11 (5)

12 (5)

9 (5)

 

 Median (IQR)

11 (8, 14)

12 (9, 15)

9 (6, 12)

 

Functional limitations

1038 (17%)

622 (16%)

416 (20%)

<0.001

Nursing home residence

577 (10%)

292 (7%)

285 (14%)

<0.001

Pre-dialysis nephrology carea

4194 (70%)

2807 (72%)

1387 (67%)

0.005

Pre-dialysis hospitalizationsb

   

<0.001

 Mean (SD)

1.6 (1.9)

1.5 (1.9)

1.7 (1.9)

 

 Median (IQR)

1.0 (0.0, 2.0)

1.0 (0.0, 2.0)

1.0 (0.0, 2.0)

 

For-Profit Facility

5171 (86%)

3407 (87%)

1764 (86%)

0.16

Facility Geographic Region

   

0.16

 Northeast

1007 (17%)

657 (17%)

350 (17%)

 

 South

2442 (41%)

1594 (41%)

848 (41%)

 

 Midwest

1341 (22%)

870 (22%)

471 (23%)

 

 West

1045 (17%)

713 (18%)

332 (16%)

 

 Unknown

146 (2%)

86 (2%)

60 (3%)

 

ESRD Cause

   

0.04

 Diabetes

2928 (49%)

1949 (50%)

749 (47%)

 

 Hypertension

2305 (38%)

1507 (38%)

798 (39%)

 

 Glomerulonephritis

246 (4%)

165 (4%)

81 (4%)

 

 Other

502 (8%)

299 (8%)

203 (10%)

 
  1. Data presented as N(%) or as indicated by row
  2. ESRD end-stage renal (kidney) disease
  3. aPre-dialysis nephrology care defined as presence of care by nephrologist prior to dialysis initiation irrespective of length of care
  4. bPre-dialysis hospitalization defined as number of hospitalizations in 12 months preceding dialysis initiation