Solute | ACDA Citrate 113 mM | CKRT Fluid (1) BBraun 4553 2 K/25Bic | CKRT Fluid (2) BBraun 4556 4 K/25Bic | 136 mM CaCl2 in 0.9% Saline |
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Calcium (mM) | | 0 | 0 | 136 |
Magnesium (mM) | | 0.75 | 0.75 | 0 |
Chloride (mM) | | 114.5 | 116.5 | 395 |
Glucose (mM) | 124 | 0 | 0 | 0 |
Sodium (mM) | 225 | 136 | 136 | 123 |
Citric Acid (mM) | 38 | | | |
Citrate3− (mM) | 75 | | | |
Potassium (mM) | | 2 | 4 | |
Bicarbonate (mM) | | 25 | 25 | |
- Footnote: In our institution, we customize the commercial CKRT fluid 1 by spiking with K-phosphate or K-chloride to final K 2, 3, or 4 mmol/L and phosphate 2.1 or 4.2 mg/dL and with NaHCO3 (default spiking: none) to final Na 136 (no added HCO3), 141 or 146 mM and HCO3 25, 30, or 35 mM (for patients who need a systemic HCO3 level > 25 and/or have moderately impaired citrate metabolism with or without moderate lactic acidosis < 10 mM). In hospitals without pharmacy support for CKRT fluid compounding the CKRT fluid 2 can be used for 4 K CKRT and phosphate could be supplemented as 15 mmol of Na-phosphate intravenous piggyback every 8 to 12 h for most patients
- Abbreviations: mM millimolar, ACDA Acid citrate dextrose A, K Potassium, Bic Bicarbonate, CaCl2 Calcium chloride