Table 2 Adjusted models: Cox model of mortality and Competing risks Regression models of ESKD and Death
From: Proton-pump inhibitor vs. H2-receptor blocker use and overall risk of CKD progression
Medication group | Cox model of Mortality HR (95% CI)* (N = 25,455, death events = 5562) | P-value | Competing Risks ESKD with death as competing risk SHR (95% CI)* (N = 25,455, ESKD events = 452, death events = 5362) | P-value | Competing Risks Death with ESKD as competing risk SHR (95% CI)* (N = 25,455, ESKD events = 452, death events = 5362) | P-value |
|---|---|---|---|---|---|---|
PPI vs. none | 0.97 (0.91, 1.03) | 0.29 | 0.93 (0.75, 1.15) | 0.49 | 0.96 (0.90, 1.02) | 0.15 |
H2 vs. none | 0.99 (0.86, 1.15) | 0.90 | 1.07 (0.67, 1.73) | 0.77 | 1.01 (0.87, 1.17) | 0.95 |
PPI vs. H2 | 0.98 (0.84, 1.13) | 0.77 | 0.87 (0.53, 1.42) | 0.57 | 0.95 (0.82, 1.11) | 0.53 |