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Table 1 PICO characteristics

From: Clinical practice guidelines standardisation of immunosuppressive and anti-infective drug regimens in UK paediatric renal transplantation: the harmonisation programme

Population

Intervention

Comparison

Outcome

Study design

Children (< 18 years) undergoing renal transplantation

Basiliximab, Tacrolimus, Prednisolone, Mycophenolate Mofetil, Azathioprine

Valganciclovir

Valaciclovir

Co-trimoxazole

Any intervention compared with any other or no intervention

Mortality, Hospitalisations, Graft failure, Acute rejection, Infections, Growth.

Randomised controlled trials (RCT),

non-randomised studies if adjusted for key confounders (age, health at baseline, co-morbidities).