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Table 1 Patient characteristics

From: Bone responsiveness to parathyroid hormone is negatively associated with parathyroid hormone-lowering drug use in patients undergoing hemodialysis: a cross-sectional study

 

N = 106

Age, years

68 [60. 75]

Female sex, n (%)

45 (42.5)

BMI, kg/m2

21.5 [19.6, 24.3]

Chronic HD vintage, years

7.9 [2.9, 12.3]

Anticoagulant during HD, n (%)

106 (100)

 None

0 (0)

 Heparin

90 (84.9)

 LMWH

10 (9.4)

 Nafamostat

6 (5.7)

Cause of ESRD, n (%)

106 (100)

 Diabetic nephropathy

34 (32.1)

 Nephrosclerosis

25 (23.6)

 Glomerulonephritis

28 (26.4)

 Others

19 (17.9)

Diabetes, n (%)

38 (35.8)

Ischemic heart disease, n (%)

27 (25.5)

Cerebrovascular disease, n (%)

18 (17.0)

CaSR agonist use, n (%)

61 (57.5)

 None

45 (42.5)

 Cinacalcet/ Evocalcet

55 (51.9)

 Etelcalcetide (i.v.)

6 (5.7)

VDRA use, n (%)

97 (91.5)

 None

9 (8.5)

 Alfacalcidol/ Falecalcitriol

48 (45.3)

 Calcitriol (i.v.)

32 (30.2)

 Maxacalcitol (i.v.)

17 (16.0)

P binder use, n (%)

90 (84.9)

 None

16 (15.1)

 Ca containing

12 (11.3)

 Non-Ca containing

55 (51.9)

 Both

23 (21.7)

Steroid use history, n (%)

13 (12.3)

β blocker use, n (%)

48, (45.3)

Statin use, n (%)

28 (26.4)

Warfarin use, n (%)

7 (6.6)

Bisphosphonate use, n (%)

14 (13.2)

Fracture history, n (%)

15 (14.2)

Ankle-brachial index

1.10 [1.03, 1.18]

Alb, g/dL

3.6 [3.4, 3.8]

cCa, mg/dL

9.1 [8.5, 9.4]

P, mg/dL

5.4 [4.5, 6.0]

iPTH, pg/mL

199.1 [119.0, 277.2]

25(OH)D, ng/mL

14.3 [11.0, 18.9]

1, 25(OH)2D, pg/mL

13 [8, 19]

BAP, μg/L

14.2 [10.8, 18.3]

TRACP-5b, mU/dL

559 [339, 833]

  1. Abbreviations: Alb Serum albumin, BAP Bone-specific alkaline phosphatase, BMI Body mass index, CaSR Calcium-sensing receptor, cCa Corrected Ca, ESRD End-stage renal disease, HD Hemodialysis, iPTH Intact parathyroid hormone, i.v. Intravenous, LMWH Low-molecular-weight heparin, P Phosphorus, TRACP-5b Tartrate-resistant acid phosphatase-5b, VDRA Vitamin D receptor activator
  2. Values are expressed as the median [interquartile range (IQR)] or as frequencies and percentages [n (%)]