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Table 5 Comparison of test results depending on the severity of AAV

From: Assessment of the correlation of commonly used laboratory tests with clinical activity, renal involvement and treatment of systemic small-vessel vasculitis with the presence of ANCA antibodies

Disease form

ANCA(IU/ml)

WBC(x10,0\cr^9/l)

Hb(g/dl)

PLT(x10,0\cr^9/l)

ESR(mm/1 h)

CRP(mg/dl)

localized and early systemic n = 6

89,0(22,2;161,5)

11,49(8,75;14,6)

11,7(10,2;12,0)

240,5(153,7;328)

23,0(14,0;37,2)

0,25(0,1;1,75)

generalized n = 10

54,0(18,9;97,7)

8,9(7,98;11,3)

10,9(8,5;12,5)

262,5(232;451,7)

43,5(24,7;85,5)

1,4(0,35;3,9)

severe n = 12

53,0(5,92;171,5)

10,3(8,92;15,6)

8,65(7,7;10,1)

285,0(186;315,7)

85,0(57;111)

6,9(2,17;18)

P *

0,661

0,285

0,009

0,577

0,007

0,006

P**

0,685

0,639

0,003

0,685

0,002

0,001

Disease form

PCT(ng/ml)

Albumin(g/dl)

Fibrinogen(mg/dl)

D-dimer(µg/ml)

C3(mg/dl)

C4 (mg/dl)

localized and early systemic n = 6

0,04(0,027;0,11)

4,3(3,9;4,5)

324(255;436)

1,08(0,49;4,04)

113,5(100;127)

28(23,5;29)

generalized n = 10

0,07(0,05;0,27)

3,65(3,15;4,37)

426(341;460)

0,77(0,48;2,39)

113,5(104;135)

22(17,7;24)

severe n = 12

0,91(0,4;2,94)

3,2(2,95;3,7)

590(485;716)

8,5(2,83;17,3)

124,0(98;134)

22(18;30)

P *

0,000

0,043

0,009

0,001

0,966

0,292

P**

0,000

0,013

0,001

0,001

0,875

0,333

  1. Values are median (IQR)
  2. P * in the Kruskal-Wallis test
  3. P** in the Jonckheere-Terpstra test for the trend