Fig. 1

Representative histopathologic sections from a renal biopsy of 25 glomeruli. Light microscopy (A–D) shows cellular fibrous crescents, cellular crescents and tubular atrophy, interstitial fibrosis, and massive infiltration of lymphocytes and monocytes. Electron microscopy (E) shows a slight increase of mesangial matrix and a small amount of electron density scattered in the mesangial area. A, Periodic acid Schiff (PAS) staining (400×). B, Periodic-acid silver methenamine (PASM) staining (400×). C, Masson staining (400×). D, hematoxylin-eosin staining (200×). E, electron microscopy (4000×)