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Table 4 The results of multivariate Cox proportional hazards regression analysis

From: Reduced serum albumin as a risk factor for poor prognosis in critically ill patients receiving renal replacement therapy

Variable

28-d mortality (HR 95%CI, p)

90-d mortality (HR 95%CI, p)

Model 1

 Alb

0.66 (0.57, 0.76) < 0.0001

0.62 (0.55, 0.71) < 0.0001

 Alb(quartile)

  Q1

1.0

1.0

  Q2

0.93 (0.73, 1.18) 0.5395

0.84 (0.67, 1.05) 0.1222

  Q3

0.75 (0.59, 0.96) 0.0219

0.69 (0.55, 0.86) 0.0012

  Q4

0.56 (0.43, 0.72) < 0.0001

0.49 (0.38, 0.62) < 0.0001

  P for trend

< 0.0001

< 0.0001

Model 2

 Alb

0.66 (0.57, 0.76) < 0.0001

0.62 (0.55, 0.71) < 0.0001

 Alb(quartile)

  Q1

1.0

1.0

  Q2

0.92 (0.73, 1.17) 0.5021

0.84 (0.68, 1.05) 0.1289

  Q3

0.75 (0.59, 0.96) 0.0220

0.69 (0.55, 0.86) 0.0012

  Q4

0.55 (0.43, 0.72) < 0.0001

0.49 (0.38, 0.62) < 0.0001

  P for trend

< 0.0001

< 0.0001

Model 3

 Alb

0.63 (0.50, 0.80) 0.0001

0.63 (0.51, 0.78) < 0.0001

 Alb(quartile)

  Q1

1.0

1.0

  Q2

0.71 (0.50, 1.02) 0.0622

0.66 (0.47, 0.92) 0.0152

  Q3

0.62 (0.44, 0.88) 0.0076

0.63 (0.46, 0.87) 0.0054

  Q4

0.52 (0.35, 0.76) 0.0008

0.52 (0.37, 0.74) 0.0003

  P for trend

0.0007

0.0006

  1. Model 1 adjust for: none
  2. Model 2 adjust for: age; sex
  3. Model 3 adjust for: age, sex, myocardial infarction, congestive heart failure, cerebrovascular disease, peripheral vascular disease, dementia, diabetes, hypertension, COPD, CRP, GFR, K+, HCO3-, phosphate, BMI, MAP, WBC, Hb, BUN, Cr, mechanical ventilation, CCI, APACHE II score, SOFA score, CRRT causes, AKI causes
  4. Q1:0.00–2.10, Q2:2.20–2.50, Q3:2.60–2.90, Q4:3.00–5.90
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BMC Nephrology

ISSN: 1471-2369

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