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Table 5 The results of subgroup analysis based on continuous renal replacement therapy (CRRT) causes

From: Reduced serum albumin as a risk factor for poor prognosis in critically ill patients receiving renal replacement therapy

Variable

28-d mortality (HR 95%CI, p)

90-d mortality (HR 95%CI, p)

Volume overload

 Model 1

  Alb

0.48 (0.31, 0.76) 0.0018

0.45 (0.28, 0.71) 0.0006

 Model 2

  Alb

0.47 (0.29, 0.75) 0.0016

0.45 (0.28, 0.71) 0.0006

 Model 3

  Alb

0.10 (0.02, 0.39) 0.0009

0.15 (0.05, 0.43) 0.0005

Metabolic acidosis

 Model 1

  Alb

0.59 (0.44, 0.80) 0.0006

0.61 (0.47, 0.80) 0.0003

 Model 2

  Alb

0.62 (0.46, 0.84) 0.0017

0.63 (0.49, 0.83) 0.0008

 Model 3

  Alb

0.24 (0.11, 0.51) 0.0002

0.28 (0.15, 0.53) 0.0001

Oliguria

 Model 1

  Alb

0.78 (0.60, 1.03) 0.0785

0.76 (0.59, 0.96) 0.0227

 Model 2

  Alb

0.79 (0.61, 1.04) 0.0974

0.76 (0.60, 0.97) 0.0290

 Model 3

  Alb

1.02 (0.60, 1.73) 0.9304

0.89 (0.56, 1.41) 0.6301

Hyperkalemia

 Model 1

  Alb

0.66 (0.37, 1.20) 0.1734

0.66 (0.39, 1.12) 0.1208

 Model 2

  Alb

0.70 (0.39, 1.28) 0.2514

0.71 (0.41, 1.22) 0.2104

 Model 3

  Alb

---a

---a

Uremia

 Model 1

  Alb

0.54 (0.30, 0.95) 0.0316

0.33 (0.19, 0.58) 0.0001

 Model 2

  Alb

0.49 (0.27, 0.91) 0.0244

0.33 (0.19, 0.59) 0.0001

 Model 3

  Alb

---a

---a

Other

 Model 1

  Alb

0.73 (0.54, 0.98) 0.0386

0.66 (0.50, 0.87) 0.0032

 Model 2

  Alb

0.74 (0.55, 1.00) 0.0467

0.65 (0.49, 0.87) 0.0037

 Model 3

  Alb

0.44 (0.25, 0.79) 0.0058

0.43 (0.25, 0.74) 0.0022

  1. Model 1 adjust for: none
  2. Model 2 adjust for: age; sex
  3. Model 3 adjust for: age, sex, myocardial infarction, congestive heart failure, cerebrovascular disease, peripheral vascular disease, dementia, diabetes, hypertension, COPD, CRP, GFR, K+, HCO3-, phosphate, BMI, MAP, WBC, Hb, BUN, Cr, mechanical ventilation, CCI, APACHE II score, SOFA score, AKI causes
  4. a: The model failed because of the small sample size