Endpoint / Lock type | Events | Patients | HR | 95%CI | p-value |
---|---|---|---|---|---|
Primary outcome | |||||
Citrate 4% or 30% | 68 | 308 | Ref. | ||
Citrate 46.7% | 239 | 1110 | 0.96 | 0.73–1.26 | 0.76 |
Taurolidine | 12 | 96 | 0.34 | 0.19–0.64 | < 0.001 |
Secondary outcome – infection | |||||
Citrate 4% or 30% | 30 | 308 | Ref. | ||
Citrate 46.7% | 120 | 1110 | 1.10 | 0.74–1.64 | 0.64 |
Taurolidine | 6 | 96 | 0.36 | 0.15–0.88 | 0.02 |
Secondary outcome – catheter malfunction | |||||
Citrate 4% or 30% | 38 | 308 | Ref. | ||
Citrate 46.7% | 119 | 1110 | 0.85 | 0.59–1.23 | 0.39 |
Taurolidine | 6 | 96 | 0.33 | 0.14–0.79 | 0.01 |