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Table 2 Univariate and multivariate analysis of risk factors associated with CKD

From: Prevalence and risk factors of chronic kidney disease in an HIV positive Mexican cohort

Variable

Univariate

Relative Risk (95%CI)

P-value

Multivariate

Relative Risk (95%CI)

P-value

Age > 30 years (n/%)

3.9 (1.2–13)

0.008

8.47 (1.5–46.8)

0.014

HIV-1 Viral Load (≥ 100,000 copies/mL)

2.7 (1.2–6.1)

0.019

4.6 (1.2–16.9)

0.020

CD4+ T cells < 200 cells/μL (n/%)

4 (1.2–13)

0.007

5.2 (1.2–12)

0.011

Clinical stage C

3.5 (1.9–7.3)

0.002

-

ns

Coinfections:

 Hepatitis C virus (HCV)

3.8 (1.8–7.9)

0.015

5.6 (3.6–9.4)

0.001

M. tuberculosis

4.3 (2.2–8.5)

0.003

33 (1.92–56.5)

0.016

  1. Multivariate analysis considering the following variables: use of Antiretroviral Therapy (ART), age, gender, school grade, clinical stage, level of CD4+ T cells, level of viral load, CD4/CD8 ratio, HCV Hepatitis B Virus (HBV) or Syphilis coinfections, Tuberculosis infection, serum albumin levels, Body Mass Index (BMI), concomitant drugs, tobacco, alcohol, or drugs use. Cox and Snell R-squared: 0.471; p = 0.001. CI Confidence interval