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Table 3 IVIM parameters between rat groups at different time

From: Non-invasive investigation of early kidney damage in streptozotocin-induced diabetic rats by intravoxel incoherent motion diffusion-weighted (IVIM) MRI

 

0 week

4 week

8 week

12 week

CO

D

Control

176.55±12.42

155.83±13.12

151.33±9.79

176.67±20.50

DM

164.73±15.14

176.50±20.25

1778.67±18.15

173.33±17.70

t/P

0.43/0.530

9.07/0.013

1.31/0.279

0.49/0.501

D*

Control

11.01±2.66

11.70±1.49

10.37±1.06

12.40±1.24

DM

10.48±1.99

17.81±2.23

15.40±5.46

14.07±2.31

t/P

1.02/0.336

1.07/0.325

1.70/0.222

2.65/0.135

f

Control

31.20±4.99

33.18±2.00

33.85±2.14

35.67±4.33

DM

27.05±5.40

2.53±4.18

29.53±4.02

32.73±1.13

t/P

0.67/0.434

0.06/0.817

0.04/0.850

0.10/0.762

ADC

Control

178.79±4.48

216.17±9.07

199.50±5.96

230.83±9.52

DM

176.00±8.32

210.17±11.43

224.33±5.47

214.50±13.40

t/P

1.39/0.266

2.13/0.175

8.98/0.013

5.39/0.043

OS

D

Control

167.76±11.81

171.83±15.57

157.33±9.79

176.67±20.51

DM

165.00±9.27

184.33±14.36

178.67±18.15

173.33±17.7

t/P

0.27/0.613

3.34/0.098

2.55/0.142

0.13/0.730

D*

Control

15.96±2.39

16.27±2.84

10.28±0.81

13.20±5.68

DM

14.98±3.60

17.15±5.10

13.78±4.41

11.37±4.04

t/P

0.02/0.896

1.49/0.251

0.82/0.388

1.54/0.243

f

Control

24.85±3.00

32.43±5.17

28.20±3.22

34.35±3.46

DM

23.15±2.83

30.35±4.16

29.53±3.17

30.65±3.84

t/P

0.16/0.698

0.12/0.738

1.69/0.233

0.08/0.790

ADC

Control

176.09±10.69

213.67±9.48

194.00±6.00

233.67±8.82

DM

177.00±7.46

213.33±9.03

220.67±3.98

210.17±11.62

t/P

0.02/0.899

3.33/0.098

1.62/0.231

23.02/0.001

IS

D

Control

209.11±15.09

187.67±14.46

175.33±11.55

194.00±21.43

DM

210.0±15.58

187.33±13.52

180.50±15.50

183.00±9.96

t/P

0.60/0.475

0.02/0.891

0.78/0.398

0.65/0.438

D*

Control

16.57±1.27

16.60±1.19

10.12±1.61

10.86±1.16

DM

14.44±3.07

15.78±3.62

11.30±3.61

16.13±3.14

t/P

2.16/0.172

0.10/0.754

0.03/0.864

2.73/0.129

f

Control

18.13±2.35

28.05±5.68

30.93±4.18

34.53±8.28

DM

17.28±3.12

29.82±3.42

33.52±3.86

30.03±3.79

t/P

0.71/0.419

0.03/0.858

1.19/0.301

0.03/0.869

ADC

Control

211.13±5.06

228.50±18.09

196.17±21.87

260.50±17.90

DM

210.00±4.15

214.17±10.21

219.50±16.81

209.50±9.85

t/P

0.06/0.812

0.68/0.429

0.00/1.000

26.81/<0.001

IM

D

Control

202.50±10.86

200.67±8.73

203.83±9.09

220.83±49.14

DM

207.83±4.54

224.50±9.33

223.17±41.97

233.83±33.23

t/P

1.23/0.290

20.86/0.001

1.22/0.300

0.29/0.600

D*

Control

15.02±1.68

13.60±2.84

13.84±2.44

12.20±1.44

DM

15.73±2.67

14.68±2.90

17.50±3.37

17.48±1.96

t/P

0.39/0.550

0.43/0.530

4.63/0.057

28.23/<0.001

f

Control

12.80±1.20

18.15±3.54

19.13±2.03

17.26±4.02

DM

13.60±2.65

25.50±1.58

25.51±15.02

20.53±7.26

t/P

0.45/0.520

21.59/0.001

1.06/0.330

0.93/0.360

ADC

Control

218.67±7.87

219.17±8.45

221.33±6.25

222.50±7.58

DM

215.00±8.37

264.17±17.03

246.33±33.27

246.00±27.26

t/P

0.61/0.450

33.61/<0.001

3.27/0.100

4.14/0.070

  1. Note: D true diffusivity, D* pseudodiffusion coefficient, f perfusion fraction, ADC apparent diffusion coefficient. Data are presented as the mean ± standard deviation. The P values in bold type are of statistical significance. D, ADCs are presented in × 10−5 mm2/s, D* is presented in × 10−3 mm2/s, and f is presented as a percentage. CO renal cortex, OS outer stripe of the outer medulla, IS inner stripe of the outer medulla, IM internal medulla
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BMC Nephrology

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