Non-invasive investigation of early kidney damage in streptozotocin-induced diabetic rats by intravoxel incoherent motion diffusion-weighted (IVIM) MRI

Table 4 Correlation analysis between IVIM parameters and IV collagen expression, Urine volume, BUN, and Scr

	IV collagen		Urine volume		BUN		Scr
	r	P	r	P	r	P	r	P
D_CO	0.146	0.496	0.34	0.104	0.228	0.284	0.046	0.832
D*_CO	0.115	0.592	0.527	0.033^£	0.617	0.005^£	0.311	0.14
f_co	0.347	0.097	0.276	0.192	0.339	0.105	0.313	0.136
ADC_IS	-0.202	0.344	0.275	0.193	0.108	0.617	0.061	0.778
ADC_IM	0.282	0.182	0.329	0.116	0.557	0.019^£	0.054	0.801
D*_IM	0.19	0.373	0.293	0.165	0.163	0.445	0.248	0.242
f_IM	0.232	0.275	0.132	0.539	0.527	0.033^£	-0.055	0.799

Note: D true diffusivity, D* pseudodiffusion coefficient, f perfusion fraction, ADC apparent diffusion coefficient. The P values in bold type are of statistical significance. D, ADC are presented in × 10⁻⁵ mm²/s, D* is presented in × 10⁻³ mm²/s, and f is presented as a percentage. CO renal cortex, OS outer stripe of the outer medulla, IS inner stripe of the outer medulla, IM internal medulla. ^£: P value corrected by Bonferroni

ISSN: 1471-2369