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Table 1 Demographic and clinical profile of ESKD patients according to the presence or absence of CVD

From: LDLR gene polymorphism (rs688) affects susceptibility to cardiovascular disease in end-stage kidney disease patients

Variables

ESKD CVD+

ESKD CVD-

p value

N

552

248

 

Gender (M/F)

306/246

119/129

0.053

Age at study (years)

67.4 ± 14.2

58.3 ± 15.3

< 0.001

Years on dialysis

4.8 ± 2.9

5.1 ± 3.6

0.210

Diabetes mellitus (%)

198 (36)

55 (22)

0.001

Hypertension (%)

420 (76)

119 (48)

< 0.001

BMI (kg/m2)

27.2 ± 5.3

25.9 ± 5.1

0.001

SBP (mmHg)

146 ± 9

143 ± 11

<  0.001

DBP (mmHg)

83 ± 7

81 ± 12

0.003

Total cholesterol (mmol/l)

4.7 ± 2.3

4.8 ± 1.7

0.539

HDL cholesterol (mmol/l)

1.2 ± 0.4

1.3 ± 0.5

0.002

Triglycerides (mmol/l)

1.8 ± 0.9

1.6 ± 0.9

0.004

Serum creatinine (μmol/l)

761 ± 147

782 ± 164

0.072

  1. Values are presented as mean ± SD or numbers (%). ESKD, end-stage kidney disease. CVD Cardiovascular disease, BMI Body mass index. SBP Systolic blood pressure, DBP Diastolic blood pressure. Variable values determined by Student’s t-test for continuous and Mann Whitney test for discrete variables