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Table 2 Genotype and allele distribution of rs688 polymorphism in the LDLR gene in ESKD patients and controls

From: LDLR gene polymorphism (rs688) affects susceptibility to cardiovascular disease in end-stage kidney disease patients

 

Genotypes

MAF

OR (95% CI)

N

CC

CT

TT

 

T allele

TT genotypea

ESKD patients

800

184 (23)

424 (53)

192 (24)

0.50

2.2 (1.87–2.6) p < 0.001

5.84 (3.94–8.65) p < 0.001

Controls

500

224 (45)

236 (47)

40 (8)

0.32

ref.

ref.

  1. ESKD, end-stage kidney disease.. LDLR, low density lipoprotein receptor. MAF, minor allele frequency. Genotype distribution is shown as numbers (%). Hardy-Weinberg equilibrium: χ2 = 4.219, p = 0.039 for control group; χ2 = 2.890, p = 0.089 for ESRD patients. aCalculated versus CC genotype
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BMC Nephrology

ISSN: 1471-2369

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