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Table 3 Genotype and allele distribution of rs688 polymorphism in the LDLR gene in subgroups of ESKD patients

From: LDLR gene polymorphism (rs688) affects susceptibility to cardiovascular disease in end-stage kidney disease patients

 

Genotypes

MAF

OR (95% CI)

N

CC

CT

TT

 

T allele

TT genotypea

ESKD CVD+

552

60 (11)

326 (59)

166 (30)

0.60

3.40 (2.71–4.26) p < 0.0001

13.2 (7.87–22.09) p < 0.0001

ESKD CVD-

248

124 (50)

98 (39)

26 (11)

0.30

ref.

ref.

  1. ESKD End-stage kidney disease. LDLR Low density lipoprotein receptor. CVD Cardiovascular disease. MAF Minor allele frequency. Genotype distribution is shown as numbers (%). aCalculated versus CC genotype
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BMC Nephrology

ISSN: 1471-2369

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