Oral sodium bicarbonate in people on haemodialysis: a randomised controlled trial

BMC Nephrology

Table 2 Treatment dose and electrolytes in intervention and control groups

		No treatment		Week 5-8			Week 13-16			Final dose
		Mean	SD	Mean	SD	p value^a	Mean	SD	p value^a			p value^b
Intervention (N = 16)
Bicarbonate dose (g/day)		0.0	0.0	2.2	0.3		3.7	0.5		3.7	0.5
Potassium	Pre HD	4.96	0.62	4.83	0.40	0.038*	4.78	0.55	0.08	4.79	0.49	0.07
	Post HD	3.06	0.37	3.22	0.24	0.63	3.07	0.36	0.61	3.21	0.32	0.70
	ID change	1.90	0.60	1.61	0.29	0.08	1.72	0.55	0.13	1.69	0.49	0.032*
Bicarbonate	Pre HD	18.15	1.35	20.03	1.93	0.002*	20.10	1.91	< 0.001*	20.27	1.88	< 0.001*
	Post HD	24.59	1.67	24.77	1.38	0.05	24.15	1.00	0.08	24.39	1.23	0.66
	ID change	−6.45	1.91	−4.73	1.97	0.12	−4.05	1.48	< 0.001*	− 4.12	1.53	< 0.001*
Dialysate K = 1 (%)^c		39.1		34.4		0.71	40.0		0.74	40.3		0.88
Control (N = 20)
Potassium	Pre HD	5.22	0.60	5.24	0.69		5.15	0.62
	Post HD	3.14	0.35	3.27	0.42		3.13	0.31
	ID change	2.08	0.63	1.97	0.76		2.03	0.60
Bicarbonate	Pre HD	18.02	1.55	18.16	1.47		16.77	1.83
	Post HD	24.07	1.21	23.89	1.23		23.29	1.62
	ID change	−6.05	1.35	−5.73	1.77		−6.52	1.64
Dialysate K = 1 (%)^c		38.8		43.4			36.1

ISSN: 1471-2369