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Table 3 Histopathologic findings of IgG positive and IgG negative patients

From: The relationship between glomerular IgG staining and poor prognostic findings in patients with IgA nephropathy: the data from TSN-GOLD working group

 

IgG positive patients (n: 179)

IgG negative patients

(n: 764)

p

Total glomerulus number

18 ± 10

17 ± 10

NS

Global sclerotic glomerulus number

4 ± 4

4 ± 4

NS

Segmental sclerotic glomerulus number

2 ± 3

1 ± 2

NS

Cellular crescent number

0 ± 1

0 ± 1

NS

Fibrocellular crescent number

0 ± 1

0 ± 2

NS

Basal membrane thickening

22.9%

20.9%

NS

Mesangial proliferation

86.2%

86.4%

NS

Endocapillary proliferation

24.2%

18.3%

NS

Interstitial inflammation

72.0%

74.7%

NS

Tubular atrophy/interstitial fibrosis

T0

58.5%

41.3%

< 0.05

T1

35.3%

44.7%

< 0.05

T2

6.2%

11%

NS

IgA staining

(+)

5.6%

5.9%

NS

(++)

27.5%

33.5%

NS

(+++)

68.6%

60.5%

NS

Mesangial hypercellularity

M0

23.5%

22.2%

NS

M1

76.5%

78.8%

NS

Endocapillary hypercellularity

E0

66.4%

78.7%

NS

E1

33.6%

21.3%

NS

Segmental glomerulosclerosis

S0

44.9%

39.5%

NS

S1

55.1%

60.5%

NS