Fig. 2

Mean serum potassium to dialysate potassium gradient (mmol/L) during the 4-week evaluation period. Baseline (visit 1, day −7) mean (SD) potassium gradient was comparable between the treatment arms: SZC 3.78 (0.59) mmol/L versus placebo 3.73 (0.64) mmol/L. Error bars represent 95% CIs. All estimates and 95% CIs in the 4-week evaluation period are obtained from a linear model with gradient as response and treatment as the single covariate. The mean for each treatment group is the least-squares mean from this model. The model was fitted for each visit separately. CI, confidence interval; SD, standard deviation; SZC, sodium zirconium cyclosilicate