Skip to main content

Table 1 Patient demographics between groups

From: High-dose versus low-dose iron sucrose in individuals undergoing maintenance haemodialysis: a retrospective study

Variable

HD (nā€‰=ā€‰760)

LD (nā€‰=ā€‰740)

P-value

Aged (years)

54(42ā€“64)

54(40ā€“66)

0.174a

Sex male/female

420/340

414/326

0.213b

Median duration of dialysis (months)

6.2(3.2ā€“9.7)

6.1(3.1ā€“9.5)

0.151a

BMId, kg/m2

26.2(21.1ā€“31.4)

26.3(21.6ā€“31.8)

0.112a

Blood pressurede (mmHg)

Ā Ā 

0.919c

ā€ƒSystolic

149(120ā€“174)

148(115ā€“182)

Ā 

ā€ƒDiastolic

72(59ā€“90)

73(60ā€“89)

Ā 

Hemoglobind (g/dl)

10.4(8.5ā€“12.1)

10.8(8.1ā€“12.7)

0.346a

Median serum ferritin concentration (Ī¼g/l)

221(126ā€“297)

220(124ā€“298)

0.109a

Median transferrin saturation (%)

21 (14ā€“25)

21 (13ā€“25)

0.824a

Median C-reactive protein level (mg/l)

6.3 (3.1ā€“14.6)

6.4 (3.2ā€“15.8)

0.472a

Median dose of ESA (IU/wk)

9000 (4000ā€“11,000)

9000 (4000ā€“11,000)

0.163a

Vascular access, n (%)

Ā Ā 

0.468c

ā€ƒDialysis catheter

284(37.4)

290(39.2)

Ā 

ā€ƒArteriovenous fistula or graft

476(62.6)

450(60.8)

Ā 

Cardiovascular disease, n (%)

Ā Ā 

0.537c

ā€ƒPrior myocardial infarction

64(8.4)

74(10.0)

Ā 

ā€ƒHyperlipidemia

186(24.5)

196(26.5)

Ā 

ā€ƒAtrial fibrillation

76(10.0)

53(7.2)

Ā 

ā€ƒHypertension

367(48.3)

342(46.2)

Ā 

ā€ƒHeart failure

67(8.8)

75(10.1)

Ā 

Diabetes, n (%)

216 (28.4)

202 (27.3)

Ā 

Primary cause of kidney failure, n (%)

Ā Ā 

0.200c

ā€ƒDiabetic nephropathy

221(11)

200(27.0)

Ā 

ā€ƒGlomerular disease

143(19)

141(19.0)

Ā 

ā€ƒHypertension

287(26)

270(36.5)

Ā 

ā€ƒTubulointerstitial diseasef

65(15)

76(10.3)

Ā 

ā€ƒPolycystic kidney disease

30(21)

33(4.5)

Ā 

ā€ƒUnclear

14(8)

20(2.7)

Ā 
  1. HD High-dose iron sucrose administered proactively, LD Low-dose iron sucrose administered reactively, BMI Body mass index, ESA Erythropoiesis-stimulating agent
  2. aIndependent-Samples t-test
  3. bChi-square test
  4. cMann-Whitney U test
  5. dIQR represents interquartile range (25th to 75th percentile)
  6. eMeasurements were done prior to hemodialysis
  7. fTubulointerstitial disease included pyelonephritis, reflux nephropathy, and obstructive uropathy