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Table 3 Post-transplant complications and kidney transplant outcomes in the studied population

From: Clinical outcomes and temporal trends of immunological and non-immunological rare diseases in adult kidney transplant

 

RDsKT

n = 350

nRDsKT

n = 322

P

Glomerulonephritis, N. (%)

51 (14.6)

31 (9.6)

0.050

Recurrent, N.

30

14

 

De novo, N.

11

10

 

Undetermined, N.

10

7

 

Rejection (main histologic diagnosis)a, N. (%)

66 (18.9)

62 (19.3)

0.900

AMR, N.

47

39

 

TCMR, N.

19

23

 

Infection (≥ 1 episode), N. (%)

223 (63.7)

234 (72.7)

0.013

UTI, No. (%)

130 (37.1)

133 (41.3)

0.269

Recurrent UTI, N. (%)

47 (13.4)

39 (12.1)

0.610

Urosepsis, N. (%)

27 (7.7)

36 (11.1)

0.124

Viral infections, N. (%)

96 (27.4)

114 (35.4)

0.026

Tumors (≥ 1 episode), N. (%)

52 (14.9)

58 (18.0)

0.270

Skin tumors, N. (%)

28 (8.0)

27 (8.4)

0.856

Solid tumors, N. (%)

24 (6.8)

31 (9.6)

0.191

Hematolymphoid tumors, N. (%)

1 (0.3)

4 (1.2)

0.149

Post-transplant diabetes, N. (%)

54 (15.4)

54 (16.8)

0.640

Post-transplant dysmetabolism, N. (%)

102 (29.1)

82 (25.5)

0.290

Hematologic complications, N. (%)

65 (18.6)

60 (18.6)

0.980

Urologic complications, N. (%)

54 (15.4)

50 (15.5)

0.970

Vascular complications, N. (%)

30 (8.6)

40 (12.4)

0.100

Transplant failure, N. (%)

58 (16.6)

57 (17.7)

0.700

Chronic AMR, N.

7

14

 

Acute rejection, N.

5

6

 

Glomerulonephritis (recurrent), N.

13

6

 

Glomerulonephritis (de novo), N.

2

1

 

Interstitial fibrosis/tubular atrophy, N.

4

9

 

Deceases with functioning kidney transplant, N. (%)

23 (6.6)

28 (8.7)

0.300

Cardiovascular, N.

8

5

 

Infection/sepsis, N.

6

14

 

Cancer, N.

6

7

 

Other, N.

3

2

 
  1. AMR Antibody-mediated rejection, TCMR T-cell-mediated rejection, UTI Urinary Tract Infections
  2. a Overall, rejection episodes observed in RDsKTs and nRDsKTs were 105 (76 [72.4%] AMR and 25 [23.8%] TCMR) and 90 (62 [68.9%] AMR and 26 [28.9%] TCMR), respectively