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Table 4 Multiple Logistic Regression Models Predicting Mortality and Acute Kidney Injury in the ICU Population Performed after Propensity Score Matching (2:1) (n = 534)

From: High dose intravenous vitamin C treatment in Sepsis: associations with acute kidney injury and mortality

a. Acute Kidney Injury

b. Mortality

Variable

Adjusted-OR (95% CI)

p-value

Adjusted-OR (95% CI)

p-value

Age (years)

1.02 (1.01, 1.04)

< 0.001

1.03 (1.007, 1.04)

0.01

Length of ICU Stay (hours)

1.003 (1.001, 1.004)

<.001

1.001 (1.000, 1.002)

0.05

Insurance (ref = Other)

0.93 (0.56, 1.54)

0.78

1.51 (0.68, 3.33)

0.31

Race (ref = White)

 Black

1.47 (0.99, 2.19)

0.04

1.56 (0.94, 2.60)

0.85

 Other/Unknown

0.71 (0.28, 1.78)

0.24

2.77 (0.88, 8.73)

0.16

Biological Sex (ref = Male)

0.77 (0.52, 1.12)

0.17

0.67 (0.41, 1.11)

0.12

Hypertension (ref = No)

0.72 (0.49, 1.08)

0.11

1.18 (0.70, 1.96)

0.54

Diabetes (ref = No)

1.39 (0.68, 2.83)

0.37

0.47 (0.16, 1.38)

0.17

Vasoactive Drug Use* (ref = No)

1.37 (0.84, 2.24)

0.20

0.90 (0.50, 1.63)

0.72

IV vitamin C (ref = No)

1.61 (1.09, 2.39)

0.02

0.79 (0.48, 1.31)

0.36

AKI

  

2.01 (1.12, 3.59)

0.02

  1. AKI Acute Kidney Injury
  2. *Vasoactive drug use was defined as having received at least one of the following: Dobutamine, Dopamine, Epinephrine, Norepinephrine, Phenylephrine, or Vasopressin