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Table 2 Demographic, clinical and laboratory parameters in primary glomerulonephritis

From: The spectrum of biopsy-proven glomerular diseases in a tertiary Hospital in Southern Brazil

 

MCD

FSGS

MN

MPGN

IgAN

MesPGN

P value

Age (years, %)

      

0.0121

 18-35

57.7

40.5

20.7

30.4

51.3

50

 

 36-50

19.2

27.6

24.1

26.1

26.3

33.3

 

 51-65

19.2

25

37.9

21.6

17.1

8.3

 

  > 65

3.8

6.9

17.2

21.8

5.3

8.3

 

Sex (%)

      

0.03

 Female

73.1

39.7

50

56.5

31.6

58.3

 

 Male

26.9

60.3

50

43.5

68.4

41.7

 

Ethnicity (%)

      

0.647

 Caucasian

80.8

89.7

91.4

95.7

93.4

91.7

 

 Afro-descendant

19.2

9.5

8.6

4.3

5.3

8.3

 

 Amerindian

0

0.9

0

0

1.3

0

 

DM (%)

10

9.7

14.7

6.7

11.3

0

0.960

SAH (%)

63.6

84.2

94.1

93.3

81.5

83.3

0.173

Weight

72 ± 12

73 ± 15

73 ± 19

79 ± 10

78 ± 15

65 ± 10

0.3952

Serum creatinine

0.8 (0.5-1.5)

1.5 (1.0-2.0)

0.9 (0.8-1.3)

2.0 (1.2-3.1)

1.7 (1.1-2.2)

1,1 (0.7-2.3)

< 0,0013

eGFR

101 (46-124)

56 (34-90)

72 (46-103)

38 (18-60)

47 (31-81)

66 (37-109)

0.001

Proteinuria

7.7 (5.6-8.8)

4.6 (2.3-7.3)

7.0 (4.3-9.9)

7.8 (2.4-9.7)

1.9 (1.1-3.7)

1.6 (0.7-2.6)

< 0.001

Serum albumin

2.1 ± 0.9

2.9 ± 0.9

2.5 ± 0.7

2.5 ± 0.7

3.8 ± 0.7

3.8 ± 0.6

< 0.001

Total Cholesterol

421 (321-522)

257 (187-392)

282 (199-344)

236 (194-317)

198 (155-233)

180 (160-225)

< 0.001

Triglycerides

221 (179-279)

179 (117-277)

194 (134-284)

235 (139-339)

130 (99-219)

176 (80-191)

0.006

C3a

143 ± 34.5

126 ± 31.3

134 ± 27.4

99 ± 43.3

114 ± 29

114 ± 33.3

< 0.001

C4b

38.8 ± 13.9

34.5 ± 12.5

34.8 ± 14.6

29.2 ± 20.2

30.5 ± 11.7

28 ± 12

0.266

Anti-HIV (N,%)c

1(6.7)

0

1(2.6)

0

1(1.9)

0

0.413

Anti-HCV (N,%)d

1(6.7)

1(1,2)

1(2,6)

0

4(7,3)

0

0.370

HbsAg (N,%)e

0

0

0

0

4(7.3)

1(12.5)

0.022

  1. DM diabetes mellitus, SAH systemic arterial hypertension, eGFR estimated glomerular filtration rate, MCD minimal change disease, FSGS focal segmental glomerulosclerosis, MN membranous nephropathy, MPGN membranoproliferative glomerulonephritis, IgAN IgA nephropathy, MesPGN mesangial proliferative glomerulonephritis
  2. 1N(%): Chi-square test
  3. 2Mean ± standard deviation: ANOVA
  4. 3Median (interquartile range): Kruskal-Wallis test
  5. Number of patients with measured serological parameters: aC3: 197; bC4: 197; canti-HIV: 214; danti-HCV: 216; eHbsAg: 214